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Mindfulness Effects on Anxiety: Disentangling the Role of Decentering and Treatment Expectations

Danielle Phinette Aafke Bos, Mike Keesman, Arent Roggeveen, Lene Vase, Andrea W.M. Evers, Kaya Peerdeman

preprint DOI: 10.31234/osf.io/z6jvq (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial using a balanced placebo design
Sample size 128
Population Adults experiencing anxiety related to the COVID-19 pandemic
Interventions Mindful decentering Sham decentering
Measures short State version of the State-Trait Anxiety Inventory
Topics Anxiety Meditation
Key findings Mindful decentering reduced anxiety from pre- to post-intervention compared with sham decentering, and the mindful group used more decentering-related words. The data provided no evidence for either an additive or an interactive effect of mindful decentering and treatment expectations on anxiety, suggesting the brief online decentering exercise reduced pandemic-related anxiety independently of expectations.

Abstract

In an online study using a balanced placebo design, we examined whether decentering, a key component of mindfulness, and expectations, a key component of placebo effects, contribute additively or interactively to reducing anxiety related to the COVID-19 pandemic. 128 adults were randomly assigned to one of four groups: told effective/mindful decentering, told effective/sham decentering, told sham/mindful decentering, told sham/sham decentering.Instructions were given using standardized audio-instructions. Current anxiety was assessed pre- and post-intervention with the short State version of the State-Trait Anxiety Inventory. The data could provide neither evidence for an additive nor an interactive effect of mindful decentering and treatment expectations on anxiety. Compared to sham decentering, mindful decentering reduced anxiety post-intervention. The mindful decentering group mentioned more decentering-related words than the sham decentering group. The findings indicate that a short, standardized, and online mindful decentering intervention can effectively decrease pandemic-related anxiety, independently of one’s expectations. These findings will inform on future research and on methods for optimizing mindfulness effects.

Comparable studies

Other randomized controlled trials on anxiety, most cited first.

Study Year Design Participants
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients 2000 Randomized controlled trial n = 145
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Cancer patients with life-threatening diagnoses and symptoms of depression and/or anxiety 2016 Randomized controlled trial n = 51
Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial Patients with cancer-related anxiety and depression 2016 Double-blind, placebo-controlled, crossover trial n = 29
Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance Hallucinogen-naïve adults reporting regular participation in religious or spiritual... 2006 Double-blind study n = 36
Pilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-Stage Cancer Adults with advanced-stage cancer and anxiety 2010 Double-blind, placebo-controlled study n = 12

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