Skip to content

Microdosing and standard‐dosing take‐home buprenorphine from the emergency department: A feasibility study

J. Moe, K. Badke, Megan Pratt, Raymond Y. Cho, P. Azar, Heather Flemming, K. Sutherland, B. Harvey, Lara Gurney, Julie Lockington, Penny Brasher, Sam Gill, Emma Garrod, Misty Bath, A. Kestler

Journal of the American College of Emergency Physicians Open October 20, 2020 DOI: 10.1002/emp2.12289 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Feasibility study Peer reviewed
Intervention Buprenorphine/naloxone
Topics Microdosing
Key points The authors propose that emergency department-initiated buprenorphine/naloxone, including a microdosing option that avoids withdrawal, may be a feasible approach to preventing overdose, and they set out to test the feasibility of delivering standard-dosing and microdosing take-home packages and of randomizing patients between them. No findings are reported in the available text.

Abstract

Emergency department (ED)–initiated buprenorphine may prevent overdose. Microdosing is a novel approach that does not require withdrawal, which can be a barrier to standard inductions. We aimed to evaluate the feasibility of an ED‐initiated buprenorphine/naloxone program providing standard‐dosing and microdosing take‐home packages and of randomizing patients to either intervention.

Citations in the library

Explore topics