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An age-period-cohort analysis of trends in psychedelic and ecstasy use in the Australian population.

G. Chan, Tianze Sun, Carmen C. W. Lim, W. Yuen, Daniel Stjepanović, Brienna N. Rutherford, Wayne Hall, Ben Johnson, J. Leung

Addictive Behaviors December 1, 2021 DOI: 10.1016/j.addbeh.2021.107216 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Repeated cross-sectional nationally representative household survey with age-period-cohort analysis Peer reviewed
Sample size 149,296
Population Australian household survey respondents aged 18 to 80 years
Topics MDMA
Key findings Past-year use of both psychedelics and ecstasy decreased with age. Ecstasy use showed significant period variation with no clear trend and a birth cohort pattern that peaked in the 1971-80 cohort before declining in the 1991-2001 cohort. Psychedelic use showed a significant upward trend across survey periods and similarly high prevalence in the three most recent birth cohorts.

Abstract

Aim: To test the age, cohort, and period effect on past-year use trends in psychedelic drugs and ecstasy.

Method: Data were from a repeated cross-sectional nationally representative household survey in Australia conducted every three years between 2001 and 2019. An age-period-cohort model was used to test the effect of age, birth cohort, and period on past year psychedelic and ecstasy use. Participants were between 18 and 80 years old at the time of the survey. The total sample size was 149,296 (Mean age = 45.8; 56% female). Past-year use of psychedelics and ecstasy were the key outcome variables. There were six birth cohorts that were derived in each survey: 1936-50, 1951-60, 1961-70, 1971-80, 1981-90, and 1991-2001. There were seven periods that coincided with survey years: 2001, 2004, 2007, 2010, 2013, 2016 and 2019. Age was treated as continuous.

Results: Past-year use of both psychedelics and ecstasy decreased with age, b = -0.87, 95% CI [-1.14, -0.61] and b = -0.84, 95% CI [-1.08, -0.60]. For ecstasy, while there was significant variation across periods (p < .001), there was no obvious trend. There was a significant birth cohort effect (p < .001), with prevalence increasing from the 1936-50 cohort, peaking in the 1971-80 cohort and then decreasing in the 1991-2001 cohort. For psychedelics, there was significant variation across periods (p < .001) with an upward trend. There was a significant birth cohort effect (p < .001), with prevalence increasing from the 1936-50 cohort to similarly high prevalence for the three most recent cohorts (1971-80, 1981-90, 1991-2001).

Conclusion: There were strong cohort and period effects in trends in the use of psychedelic and ecstasy.

Comparable studies

Other cross-sectional and survey studies on MDMA, most cited first.

Study Year Design Participants
Recreational MDMA use in Sydney: a profile of ‘Ecstasy’ users and their experiences with the drug Recreational Ecstasy users recruited via snowball peer network 1992 Cross-sectional survey n = 100
Reducedin vivobinding to the serotonin transporter in the cerebral cortex of MDMA (‘ecstasy’) users Male regular ecstasy users and well-matched controls 1999 Cross-sectional association study n = 20
Patterns of simultaneous polysubstance use in drug using university students Drug-using university students 2006 Cross-sectional survey n = 149
Patterns of recreational drug use at dance events in Edinburgh, Scotland Drug users at dance events in Edinburgh, Scotland, UK, aged 16-47, 80% between 18 and... 2001 Cross-sectional survey n = 122
Acute, sub‐acute and long‐term subjective consequences of ‘ecstasy’ (MDMA) consumption in 430 regular users Regular MDMA users 2003 Cross-sectional study n = 466

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