Ketamine for Suicidal Ideation: Results From A Recent Meta-Analysis
January 31, 2019 DOI: 10.64239/pi-qt0101 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Meta-analysis Randomized |
|---|---|
| Intervention | Ketamine |
| Duration | 7 days |
| Topics | Esketamine Ketamine |
| Key findings | Ketamine was associated with rapid reduction of suicidal ideation across 10 randomized trials, sometimes without similar reductions in depression. The effect persisted for 7 days. |
Abstract
In this meta-analysis of 10 randomized trials, ketamine was associated with rapid reduction of suicidal ideation, sometimes even without similar reductions in depression. The effect persisted for 7 days.
Comparable studies
Other systematic reviews and meta-analyses on ketamine, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| The effect of a single dose of intravenous ketamine on suicidal ideation: a systematic review and individual participant data meta-analysis Depressed patients with suicidal ideation at baseline | 2017 | Systematic review and individual participant data meta-analysis | n = 167 |
| Ketamine use: a review Ketamine users | 2011 | Systematic review | |
| Ketamine and Other NMDA Antagonists: Early Clinical Trials and Possible Mechanisms in Depression Participants with major depression in placebo-controlled, double-blind, randomized... | 2015 | Systematic review and meta-analysis | |
| Ketamine and postoperative pain – a quantitative systematic review of randomised trials Surgical patients from 25 countries | 2004 | Systematic review | n = 2,839 |
| Side-effects associated with ketamine use in depression: a systematic review. Patients with depression | 2018 | Systematic review |