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Ketamine and Suicidal Ideation

May 14, 2019 DOI: 10.64239/pi-vl1406 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Review
Intervention Ketamine
Topics Esketamine Ketamine
Key findings Ketamine rapidly reduces suicidal ideation, but long-term data are needed before clinical use.

Abstract

Several studies have shown that ketamine can lead to a rapid reduction in suicidal ideation. Ketamine’s rapid effect on suicidal ideation seems at least partially independent of its antidepressant effect. Given the lack of long-term follow-up, the concern for long-term exposure to ketamine, and the transient nature of the effect of a single-dose of ketamine, more long-term data are needed before ketamine can be used in clinical settings for the treatment of suicidal ideation.