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New psychoactive substances: kratom, DMT, serotonergic hallucinogens, dissociative drugs. The mechanism of action, psychoactive effects

Andrey V. Antsyborov

Neurology Bulletin May 10, 2023 DOI: 10.17816/nb119895 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Review Peer reviewed
Topics DMT Serotonin
Key findings The review identifies mitragynine (Kratom), dimethyltryptamine, a new generation of serotonergic hallucinogens, ketamine, and other dissociative substances as new psychoactive substances that have only been thoroughly studied in recent years, noting that such compounds can alter mental state, behavior, and social activity.

Abstract

Through the times of human culture there was a desire of using various chemical compounds, obtained from both natural plant material and artificially synthesized, for recreational purposes. These substances can cause changes in the mental state, influence the human behavior, change social activity. The review is devoted to NPS, which have only been thoroughly studied in recent years. These substances include: mitragynine (Kratom), dimethyltryptamine, a new generation of serotonergic hallucinogens, ketamine, and other dissociative substances.