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Meditation programs for adults with type 2 diabetes mellitus: A protocol for a systematic review and meta-analysis.

Jiayu Xu, Manxue Mei, Haoxiang Sun, Xiaofang Chen, Wei Zhu, Jianping Song

Medicine November 25, 2022 DOI: 10.1097/md.0000000000031459 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Systematic review protocol Randomized Peer reviewed
Population Adults with type 2 diabetes mellitus (planned inclusion criteria)
Intervention Meditation programs
Measures glycosylated hemoglobin level, fasting blood glucose level, high-density lipoprotein, low-density lipoprotein, body mass index, remission of depression and anxiety, quality of life
Topics Meditation
Key findings The authors propose a systematic review and meta-analysis to assess whether meditation programs improve glycemic control and related outcomes in adults with type 2 diabetes, arguing that prior trial evidence, while suggestive, requires confirmation. They state it will be the first review to analyze the efficacy of different types of meditation for this condition.

Abstract

Type 2 diabetes mellitus is intimately linked to chronic stress. Meditation programs belong to mind-body therapies, which could benefit patients' disease management. Though some clinical trials have proved that meditation programs have the ability to improve level of blood glucose quality of life, body mass index and blood indexes related to metabolism in individuals with type 2 diabetes mellitus, the efficacy of meditation programs needs further confirmation. Thus we will conduct this systematic evaluation and meta-analysis to summarize and analyze all the results included to obtain reliable evidence. We will search several English and Chinese databases for relevant clinical trials published up to July 2021, and randomized controlled trials or controlled trials among adults with type 2 diabetes mellitus are included. Two reviewers will extract data and assess the quality of included studies independently. The main outcomes of this research are glycosylated hemoglobin level and fasting blood glucose level. The secondary outcomes are high-density lipoprotein, low-density lipoprotein, body mass index, remission of depression and anxiety, and quality of life. Stata v.14.0 and Review Manager V5.3 will be used to synthesize and analyze all data included. Grading of Recommendations Assessment, Development, and Evaluation will be used to evaluate the quality of the assessments. Our study will be disseminated through publications in peer-reviewed journals. This systematic review is the first to analyze the efficacy of different types of meditation for type 2 diabetes mellitus, which could provide evidence for the use of mediation programs as non-drug approaches. PROSPERO CRD42021274508.

Comparable studies

Other systematic reviews and meta-analyses on meditation, most cited first.

Study Year Design Participants
Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations 2014 Meta-analysis n = 3,515
Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis Healthy subjects 2009 Systematic review and meta-analysis
The psychological effects of meditation: A meta-analysis. Nonclinical groups of adult meditators 2012 Meta-analysis n = 163
Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse Adults with recurrent depression in full or partial remission 2016 Meta-analysis of individual patient data from randomized controlled trials n = 1,258
Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials 2011 Systematic review

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