Structural connectivity of the precuneus and its relation to resting-state networks
Atsushi Yamaguchi, Tatsuya Jitsuishi
Neuroscience Research December 7, 2024 DOI: 10.1016/j.neures.2023.12.004 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Keywords | Precuneus Tractography Resting-state networks |
| Key findings | The review reports that the precuneus is functionally heterogeneous, with subfields organized along anterior-posterior and ventral-dorsal axes, and that it serves as a rich-club hub forming the structural core of brain connectivity while overlapping with the default mode network as a functional core. The authors situate their tractography-based findings within this framework to discuss possible cognitive functions and resting-state networks. |
Abstract
The precuneus is an association area in the posteromedial cortex (PMC) that is involved in high-order cognitive functions through integrating multi-modal information. Previous studies have shown that the precuneus is functionally heterogeneous and subdivided into several subfields organized by the anterior-posterior and ventral-dorsal axes. Further, the precuneus forms the structural core of brain connectivity as a rich-club hub and overlaps with the default mode network (DMN) as the functional core. This review summarizes recent research on the connectivity and cognitive functions of the precuneus. We then present our recent tractography-based studies of the precuneus and contextual these results here with respect to possible cognitive functions and resting-state networks.