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Severe Dissociative Experiences beyond Detachment in a Large Clinical Sample of Inpatients with Post-Traumatic Stress Disorder: Diagnostic and Treatment Implications

Leonhard Kratzer, S. Tschöke, Johanna Schröder, Mark E. Shevlin, Philip Hyland, Christine Eckenberger, Peter Heinz, T. Karatzias

Psychopathology July 22, 2024 DOI: 10.1159/000539740 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational study using latent profile analysis of retrospective clinical routine data Peer reviewed
Sample size 1,360
Population Severely traumatized inpatients with PTSD
Measures Childhood Trauma Questionnaire, Impact-of-Event Scale-Revised, Dissociative Experiences Scale-Taxon (DES-T)
Topics PTSD
Key findings Latent profile analysis identified three classes: PTSD, a dissociative subtype, and a third class with more complex and severe dissociative symptoms such as auditory-verbal hallucination, amnesia, and identity alteration. This third class was the most prevalent in the inpatient sample, suggesting that dissociative symptoms beyond detachment are common in severe PTSD.

Abstract

Abstract

Introduction: The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) contains a dissociative subtype of post-traumatic stress disorder (PTSD) characterized by depersonalization and derealization. Yet, there is evidence that dissociative symptoms in PTSD go beyond this kind of detachment dissociation and that some patients present with additional compartmentalization dissociation in the form of auditory-verbal hallucination, amnesia, and identity alteration.

Methods: Hence, in this study, we examined latent profiles of childhood trauma (Childhood Trauma Questionnaire), PTSD (Impact-of-Event Scale-Revised), and pathological dissociation (Dissociative Experiences Scale-Taxon; DES-T) in a large sample of severely traumatized inpatients with PTSD (N = 1,360).

Results: Results support a three-class solution of the latent profile analysis with a PTSD class, a dissociative subtype class, and a third class characterized by more complex and more severe dissociative symptoms. Importantly, in our inpatient sample of patients with severe PTSD, the latter class was found to be the most prevalent. Both the exploratory character of our retrospective analysis of clinical routine data and the use of the DES-T limit the generalizability of our findings, which require methodologically more rigorous replication.

Conclusion: In severe PTSD, dissociative symptoms beyond detachment are highly prevalent. Diagnostic and treatment implications are discussed.

Comparable studies

Other observational and cohort studies on PTSD, most cited first.

Study Year Design Participants
MDMA-Assisted Psychotherapy Using Low Doses in a Small Sample of Women with Chronic Posttraumatic Stress Disorder Women with chronic PTSD secondary to sexual assault 2008 Observational cohort n = 6
An Ambulatory Polysomnography Study of the Post-traumatic Nightmares of Post-traumatic Stress Disorder Treatment-seeking veterans, current serving military members, and emergency service... 2017 Observational study using ambulatory polysomnography n = 35
Increased Mastery Elements Associated With Imagery Rehearsal Treatment for Nightmares in Sexual Assault Survivors With PTSD. Female sexual assault survivors with chronic nightmares 2004 Observational cohort n = 44
Posttraumatic stress symptoms following near-death experiences. Persons who report near-death experiences and those who came close to death without NDEs 2001 Observational study
Impact of oral ketamine augmentation on hospital admissions in treatment-resistant depression and PTSD: a retrospective study. Outpatients with treatment-resistant depression and PTSD 2018 Retrospective review n = 37

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