MDMA-Assisted Psychotherapy Using Low Doses in a Small Sample of Women with Chronic Posttraumatic Stress Disorder
José Carlos Bouso, Rick Doblin, Magı́ Farré, Miguel Ángel Alcázar‐córcoles, Gregorio Gómez-jarabo
Journal of Psychoactive Drugs September 1, 2008 DOI: 10.1080/02791072.2008.10400637 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Sample size | 6 |
| Population | Women with chronic PTSD secondary to sexual assault |
| Intervention | MDMA-assisted psychotherapy |
| Dose | between 50 and 75 mg |
| Topics | MDMA Psychedelic-assisted therapy |
| Keywords | Posttraumatic stress Clinical psychology |
| Citations | 206 |
| Key findings | Low doses of MDMA (50–75 mg) were psychologically and physiologically safe for all six women with chronic PTSD from sexual assault. |
Abstract
The purpose of this study was to investigate the safety of different doses of MDMA-assisted psychotherapy administered in a psychotherapeutic setting to women with chronic PTSD secondary to a sexual assault, and also to obtain preliminary data regarding efficacy. Although this study was originally planned to include 29 subjects, political pressures led to the closing of the study before it could be finished, at which time only six subjects had been treated. Preliminary results from those six subjects are presented here. We found that low doses of MDMA (between 50 and 75 mg) were both psychologically and physiologically safe for all the subjects. Future studies in larger samples and using larger doses are needed in order to further clarify the safety and efficacy of MDMA in the clinical setting in subjects with PTSD.