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The Protective Role of Spirituality, Mindfulness, and Hope in Depression: A Cross-Sectional Study Among Afghan University Students

Mohammad Jawad Mirzaee

Journal of Social Sciences and Humanities January 31, 2026 DOI: 10.62810/jssh.v3i1.222 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Cross-sectional study Longitudinal Peer reviewed
Sample size 450
Population Undergraduate and master's students from four universities in Kabul, Afghanistan, during the 2025 academic year
Topics Depression Meditation
Key findings Higher spirituality and mindfulness were associated with lower depression among Afghan university students, with spirituality the strongest protective factor, while hope was not significantly related to depression. The model explained 5% of the variance in depression, and the authors argue for integrating spiritual well-being and mindfulness-based strategies into mental health promotion, though the cross-sectional design precludes causal conclusions.

Abstract

Depression is highly prevalent among university students worldwide, yet evidence from Afghanistan is limited. This study examined the protective roles of spirituality, mindfulness, and hope against depression among 450 undergraduate and master’s students from four universities in Kabul during the 2025 academic year. The sample was predominantly young adults, with 43.1% aged 18–22 years and 32.7% aged 23–27 years. Most participants were enrolled in bachelor’s programs (71.8%). Participants completed standardized questionnaires assessing depression, spiritual well-being, mindfulness, and hope. Results showed that higher levels of spirituality and mindfulness were associated with lower depression, whereas hope did not significantly relate to depression. Spirituality emerged as the strongest protective factor. Overall, the model explained 5% of the variance in depression, suggesting that additional contextual factors may also play a role. These findings highlight the importance of culturally embedded psychological resources in supporting mental health in fragile and conflict-affected environments. The study underscores the value of integrating spiritual well-being and mindfulness-based strategies into mental health promotion programs in Afghan higher education. Although causal conclusions cannot be drawn due to the cross-sectional design, these results provide a foundation for future longitudinal research and the development of culturally sensitive interventions aimed at reducing depression among young adults in Afghanistan.

Comparable studies

Other cross-sectional and survey studies on depression, most cited first.

Study Year Design Participants
Psychological flexibility mediates the relations between acute psychedelic effects and subjective decreases in depression and anxiety. International sample of people who reported having used a psychedelic 2020 Cross-sectional survey n = 985
5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) used in a naturalistic group setting is associated with unintended improvements in depression and anxiety. Adults who used 5-MeO-DMT in a group setting with structured procedures 2019 Cross-sectional survey n = 362
Psychological and neuropsychological assessment of regular hoasca users. Regular hoasca users from a U.S. branch of União do Vegetal and matched non-user controls 2016 Cross-sectional study n = 57
Adults who microdose psychedelics report health related motivations and lower levels of anxiety and depression compared to non-microdosers Self-selected microdosers and non-microdosers recruited via a mobile application 2021 Cross-sectional survey n = 8,703
Effects of Naturalistic Psychedelic Use on Depression, Anxiety, and Well-Being: Associations With Patterns of Use, Reported Harms, and Transformative Mental States. Adults with at least one lifetime psychedelic experience 2022 Cross-sectional survey n = 2,510

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