Impact of Developmental Stage on Responses to a School-Based Mindfulness Intervention
Michiko Ashitani, Yasushi Ito, Kazumi Yamamoto
Mindfulness February 26, 2026 DOI: 10.1007/s12671-026-02792-z (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational comparison of two age groups within a single-arm feasibility study Randomized Peer reviewed |
|---|---|
| Sample size | 143 |
| Population | Japanese adolescents aged 12–17; 74 junior high students (12–14) and 69 senior high students (15–17) |
| Duration | 10-week program; follow-up 2 months after intervention |
| Measures | Center for Epidemiologic Studies Depression Scale (CES-D), Warwick–Edinburgh Mental Wellbeing Scale (WEMWBS), Strengths and Difficulties Questionnaire (SDQ), Profile of Mood States, Second Edition (POMS2) |
| Topics | Meditation |
| Key findings | Senior high participants showed significant improvements on all measures after the .b program, while junior high participants did not, with between-group differences statistically significant or marginally significant. No depressive symptom worsening occurred in either group. The authors propose that developmental stage may explain divergent UK feasibility study and MYRIAD trial results. |
Abstract
Objectives: The .b (“dot be”) mindfulness program aims to reduce both internalizing and externalizing risks and to enhance well-being among adolescents. A UK-based feasibility study (FS) reported significant improvements in depressive symptoms, stress, and well-being, whereas a large-scale randomized controlled trial—the UK-based MYRIAD study (MS) found no improvements and even some negative outcomes. To assess whether developmental stage might play an explanatory role in these discrepancies, we evaluated and compared the responses to .b between two groups of Japanese adolescents, ages 12–14 and 15–17 years.
Method: A total of 143 Japanese students, 74 in junior high (JH, ages 12–14) and 69 in senior high (SH, ages 15–17), participated in the 10-week .b. Participants completed questionnaires at baseline, post-intervention, and 2 months later. Measures included the Center for Epidemiologic Studies Depression Scale (CES-D), the Warwick–Edinburgh Mental Wellbeing Scale (WEMWBS), the Strengths and Difficulties Questionnaire (SDQ), and the Profile of Mood States, Second Edition (POMS2).
Results: The SH group showed significant improvements across all measures, while the JH group did not. The differences in the degree of improvement between the two groups were statistically significant or marginally significant. No worsening of depressive symptoms was observed in either group, including among younger or high-risk subgroups.
Conclusions: These findings suggest that the response to .b may vary depending on the developmental stage of the participants, which may help explain the differing results between the FS and MS in the UK.
Comparable studies
Other non-randomized and open-label trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Mindfulness-Based Stress Reduction in Relation to Quality of Life, Mood, Symptoms of Stress, and Immune Parameters in Breast and Prostate Cancer Outpatients Early-stage breast and prostate cancer patients | 2003 | Pre-post intervention study | n = 59 |
| Exploring self‐compassion and empathy in the context of mindfulness‐based stress reduction (MBSR) Community sample | 2010 | Pre-post intervention study | |
| Mindfulness-Based Stress Reduction Lowers Psychological Distress In Medical Students Second-year medical students | 2003 | Prospective nonrandomized cohort-controlled study | n = 302 |
| Intensive meditation training, immune cell telomerase activity, and psychological mediators. Retreat participants and matched controls | 2011 | Controlled trial with wait-list control group | n = 60 |
| The Effectiveness of Mindfulness Training for Children with ADHD and Mindful Parenting for their Parents Children aged 8-12 with ADHD and their parents | 2011 | Within-group waitlist controlled trial | n = 22 |
Citations in the library
Cites 16
- Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse JAMA Psychiatry April 28, 2016
- Research Review: The effects of mindfulness‐based interventions on cognition and mental health in children and adolescents – a meta‐analysis of randomized controlled trials Journal of Child Psychology and Psychiatry October 22, 2018
- Home practice in Mindfulness-Based Cognitive Therapy and Mindfulness-Based Stress Reduction: A systematic review and meta-analysis of participants' mindfulness practice and its association with outcomes Behaviour Research and Therapy May 10, 2017
- The Empirical Status of Mindfulness-Based Interventions: A Systematic Review of 44 Meta-Analyses of Randomized Controlled Trials Perspectives on Psychological Science February 16, 2021
- Mindfulness in the school curriculum? A nationwide cluster-randomized trial of the effectiveness of implementing a mindfulness-based intervention for 9-16-year-olds students in Danish elementary schools. Social Science & Medicine August 1, 2025
and 11 more in the library