Know Your Nose: A Narrative Review of Developmental, Functional, Impact, and Importance of Nose and Nasal Breathing on Health and Emotional Wellbeing
Alireza Amirsadri, Hooman Sedighi
Preprints.org January 29, 2026 preprint DOI: 10.20944/preprints202601.2315.v1 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Narrative review |
|---|---|
| Key findings | The authors argue that nasal breathing plays a multifaceted role in human health, supporting infant development, air conditioning and immune defense, and—through nitric oxide, olfaction, and vagal stimulation—autonomic, emotional, cognitive, and consciousness-related regulation. They contend that modern scientific evidence increasingly validates traditional spiritual practices that emphasize nasal breathing, with implications for clinical practice, developmental health, and contemplative traditions. |
Abstract
This narrative review synthesizes research demonstrating the multifaceted role of nasal breathing in human health and wellbeing across developmental, physiological, immunological, and neuropsychological domains. Nasal breathing emerges as fundamental to infant development, enabling correct breastfeeding mechanics and contributing to proper maxillofacial growth. Nasal structures condition and thermoregulate inhaled air while providing immune defense through nitric oxide production in the paranasal sinuses, mucosal immune barriers, and physical particle filtration. Through nitric oxide, olfaction, and vagal stimulation, nasal breathing influences autonomic and emotion regulation, cognitive performance, and aspects of consciousness. Notably, many traditional spiritual practices, including yogic pranayama, Sufi traditions, and meditative breathing techniques, have long emphasized nasal breathing for physical and psychological wellbeing. Contemporary scientific evidence increasingly validates these ancient practices, revealing how specific breathing patterns enhance parasympathetic tone, increase heart rate variability, and promote physiological and psychological balance. This convergence of traditional wisdom and modern neuroscience affirms the import traditional spiritual practices have long attributed to nasal breathing, with implications for clinical practice, developmental health, and contemplative traditions. Understanding nasal breathing’s multifaceted role across these domains can inform interventions that work with the body’s natural regulatory mechanisms.