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Effectiveness of Mindfulness based intervention on Blood Pressure Control in Dialysis Patients: A Pilot Study

Nidhi Sharma, P. Thenmozhi

International Journal of Drug Delivery Technology April 6, 2026 DOI: 10.25258/ijddt.16.2.21 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Quasi-experimental pre-test–post-test pilot study Peer reviewed
Sample size 10
Population Patients undergoing maintenance hemodialysis at a tertiary hospital dialysis unit
Intervention Mindfulness-based stress reduction (MBSR)
Duration 8-week MBSR program
Topics Meditation
Key findings An eight-week MBSR program was associated with a significant reduction in systolic blood pressure and greater intradialytic blood pressure stability in hemodialysis patients, with group differences becoming significant from 1.5 hours into dialysis. Diastolic changes were not significant. The authors suggest MBSR could be an effective adjunct therapy for managing blood pressure in this population.

Abstract

A major global health concern, chronic kidney disease (CKD) is exacerbated by hypertension, contributing to renal impairment and increased cardiovascular risk, particularly in hemodialysis patients with intradialytic hypertension. This pilot study assessed the efficacy of mindfulness-based stress reduction (MBSR) in managing blood pressure among patients undergoing maintenance hemodialysis. Ten participants, selected from a tertiary hospital dialysis unit, were divided into experimental and control groups using a quasi-experimental pre-test–post-test design. While the control group continued with standard treatment, the experimental group engaged in an eight-week MBSR program. Blood pressure measurements were taken pre-, during, and post-dialysis using a calibrated mercury sphygmomanometer, with data analyzed using repeated measures ANOVA and independent t-tests. The results indicated a significant reduction in systolic blood pressure in the experimental group (p = 0.02), while diastolic changes were not significant. Notably, systolic, and diastolic pressures were more stable in the experimental group during dialysis, contrasting with gradual increases in the control group. These differences became significant starting at 1.5 hours (p < 0.05). Clinical and demographic factors such as age, gender, duration of illness, and cause of renal failure were correlated with post-test blood pressure outcomes. The findings suggest that MBSR could be an effective adjunct therapy for managing blood pressure and improving clinical outcomes in hemodialysis patients