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Effect of mindfulness-based stress reduction on nursing interns' death anxiety, stress, and palliative care self-efficacy during oncology end-of-life training.

Donia Elsaid Fathi Zaghamir, Ateya Megahed Ibrahim, Hala Samir Ahmed El-Husseiny

Palliative & Supportive Care September 11, 2026 DOI: 10.1017/s1478951526103447 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Quasi-experimental pre-post study Peer reviewed
Sample size 120
Population Final-year Bachelor of Science in nursing interns at Prince Sattam Bin Abdulaziz University, Saudi Arabia, during palliative and oncology rotations
Intervention Mindfulness-Based Stress Reduction (MBSR)
Duration 8-week program with weekly 2-hour sessions, a silent retreat, and daily home practice; pre- and post-intervention assessments
Measures Death Attitude Profile-Revised (DAP-R), Perceived Stress Scale (PSS-10), Frommelt Attitude Toward Care of the Dying Scale Form B (FATCOD-B)
Topics Anxiety Meditation End-of-life distress
Keywords Humans Palliative care Terminal care Attitude to death Stress, psychological Self efficacy Psychometrics Adult Saudi arabia Female Surveys and questionnaires Perceived stress Mindfulness-based stress reduction Death anxiety Nursing interns Attitudes toward dying
Key findings After the 8-week MBSR program, nursing interns showed reduced death anxiety (DAP-R 134.67 to 118.46) and perceived stress (PSS-10 20.29 to 19.41), and improved attitudes toward caring for dying patients (FATCOD-B 84.10 to 90.01). Baseline FATCOD-B scores were the strongest predictor of post-intervention attitudes. The authors argue that integrating MBSR into nursing education may better prepare interns for compassionate end-of-life care.

Abstract

Objectives: Nursing interns often experience high levels of death anxiety and stress, which can reduce their comfort and confidence in caring for dying patients. This study evaluated the effects of an 8-week Mindfulness-Based Stress Reduction (MBSR) program on death anxiety, perceived stress, and attitudes toward care of the dying among nursing interns during palliative and oncology rotations.

Methods: A quasi-experimental pre-post design was used with 120 final-year Bachelor of Science in nursing interns at Prince Sattam Bin Abdulaziz University, Saudi Arabia. Participants completed the 8-week MBSR program following Kabat-Zinn's original protocol, including weekly 2-hour sessions, a silent retreat, and daily home practice. Pre- and post-intervention assessments were conducted using the Death Attitude Profile-Revised (DAP-R), Perceived Stress Scale (PSS-10), and Frommelt Attitude Toward Care of the Dying Scale Form B (FATCOD-B). Data were analyzed using paired t-tests, effect sizes (Cohen's d), Pearson correlations, and multiple linear regression to identify predictors of post-intervention attitudes.

Results: Post-intervention, nursing interns showed a significant reduction in death anxiety (DAP-R: 134.67 ± 6.70 vs. 118.46 ± 7.85; t = 33.39, p < 0.001, d = 3.05) and perceived stress (PSS-10: 20.29 ± 2.94 vs. 19.41 ± 3.36; t = 4.25, p < 0.001, d = 0.39). Attitudes toward caring for dying patients improved significantly (FATCOD-B: 84.10 ± 4.99 vs. 90.01 ± 5.64; t = -16.95, p < 0.001, d = 1.55). Baseline FATCOD-B scores were the strongest predictor of post-intervention attitudes (β = 0.778, p < 0.001). Correlations between constructs were weak, indicating that death anxiety, perceived stress, and care attitudes represent distinct dimensions. Significance of

Results: These findings highlight that mindfulness training can enhance emotional resilience, reduce anxiety and stress, and positively shape attitudes toward caring for dying patients. Integrating MBSR into nursing education during palliative rotations may better prepare interns to provide compassionate, human-centered end-of-life care, ultimately improving patient and family experiences in terminal illness settings.

In the evidence

This study is part of the evidence base for a synthesis in the library. Here is how each one recorded it.

  • An 8-week MBSR program significantly reduced death anxiety and perceived stress and improved attitudes toward caring for dying patients.

    Synthesized

Comparable studies

Other non-randomized and open-label trials on end-of-life distress, most cited first.

Study Year Design Participants
A Phase II, Open-Label Clinical Trial of Intranasal Ketamine for Depression in Patients with Cancer Receiving Palliative Care (INKeD-PC Study) Patients with advanced cancer and moderate to severe major depressive disorder 2023 Single-arm, open-label phase II trial n = 20
Mindfulness and compassion training on daily work with patients and within the multiprofessional palliative care team: a retrospective self-assessment study Employees of a university-based specialized palliative care unit 2023 Observational cohort (pre-post self-assessment) n = 24
Intranasal Ketamine for Existential Distress in Advanced Cancer. Patients with advanced cancer receiving palliative care 2026 Secondary analysis of a clinical trial n = 15
PSilocybin for psYCHological and existential distress in PALliative care (PSYCHED-PAL): A single arm unblinded clinical trial Adults with advanced, incurable illness and estimated prognosis of 1–12 months,... 2026 Open label, single-arm clinical trial n = 20
Effects of embedded micro-mindfulness on psychological symptoms in patients with advanced cancer receiving palliative care: a prospective controlled study. Patients with advanced cancer receiving palliative care at West China Hospital 2026 Prospective, non-randomized observational study n = 243

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