Acute renal failure due to accelerated hypertension following ingestion of 3,4-methylenedioxymethamphetamine (‘ecstasy’)
Graham Woodrow, Patricia Harnden, J. H. Turney
Nephrology, Dialysis, Transplantation March 1, 1995 DOI: 10.1093/ndt/10.3.399 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | 21-year-old man |
| Intervention | 3 |
| Topics | MDMA |
| Citations | 35 |
| Key findings | The authors report that a 21-year-old man developed acute renal failure due to accelerated hypertension after ingesting ecstasy, suggesting that ecstasy can cause severe hypertension leading to kidney injury. |
Abstract
G. Woodrow, P. Harnden, J. H. Turney; Acute renal failure due to accelerated hypertension following ingestion of 3,4-methylenedioxymethamphetamine (‘ecstasy’),
Comparable studies
Other case reports and case series on MDMA, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| 'Eve' and 'Ecstasy'. A report of five deaths associated with the use of MDEA and MDMA Individuals whose deaths were associated with MDMA or MDEA use | 1987 | Case series | n = 5 |
| Pathology of deaths associated with "ecstasy" and "eve" misuse. Young white men aged 20 to 25 who died after using ring-substituted amphetamines (MDMA... | 1996 | Case series | n = 7 |
| 'Eve' and 'Ecstasy' Individuals who died after using MDMA or MDEA | 1987 | Case series | n = 5 |
| A Method of Conducting Therapeutic Sessions with MDMA Clients with clear therapeutic purpose, excluding those with serious functional... | 1998 | Case study | n = 2 |
| Diversity of Psychopathology Associated with use of 3,4-Methylenedioxymethamphetamine (‘Ecstasy’) Psychiatric patients presenting between 1990 and 1992 whose symptoms developed in the... | 1994 | Case series | n = 13 |
Citations in the library
Cited by 5
- Aortic Dissection After Ingestion of "Ecstasy" (MDMA) American Journal of Forensic Medicine & Pathology September 1, 2000
- Triggers of highly lethal seizures induced by novel stimulants: A systematic review focused on synthetic cathinones and phenethylamines. Neurotoxicology January 14, 2026
- MDMA impairs response to water intake in healthy volunteers bioRxiv (Cold Spring Harbor Laboratory)
- The agony of ecstasy: MDMA (3,4-methylenedioxymethamphetamine) and the kidney. Clinical journal of the American Society of Nephrology : CJASN November 2008
- Role of metabolites in MDMA (ecstasy)-induced nephrotoxicity: an in vitro study using rat and human renal proximal tubular cells. Archives of Toxicology October 2002