[Effects of N,N-dimethyltryptamine (DMT) on tests of psychoticism (author's transl)].
P Bickel, A Dittrich, J Schöpf
Pharmakopsychiatrie, Neuro-Psychopharmakologie January 1977 DOI: 10.1055/s-0028-1094512 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Controlled study Peer reviewed |
|---|---|
| Sample size | 38 |
| Population | Volunteers |
| Interventions | N N-dimethyltryptamine (DMT) placebo |
| Dose | 250 micrograms/kg |
| Measures | objective and performance tests measuring psychoticism according to Eysenck |
| Topics | 5-MeO-DMT DMT |
| Key points | DMT produced changes resembling those seen in endogenous psychosis on 7 of 19 objective and performance variables, most of which were tests of concentration, supporting the hypothesis that DMT shifts psychoticism scores in the same direction as endogenous psychosis. |
Abstract
In a controlled study on 38 volunteers the effects of 250 micrograms/kg N,N-dimethyltryptamine (DMT) i.m. on objective and performance tests measuring psychoticism according to Eysenck were assessed. The hypothesis was tested that subjects treated with DMT (N = 26) differ from those receiving placebo (N = 12) in the same way as endogenous psychotics differ from normals. Confirmation was obtained in 7 out of 19 variables, most of which may be considered as tests of concentration. These results are similar to those of a previous study on the effects of (-) delta9-trans-Tetrahydrocannabinol.