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Can psilocybin help a patient with chronic depression?

Zenodo (CERN European Organization for Nuclear Research) August 31, 2026 preprint DOI: 10.5281/zenodo.22215431 (opens in new tab)

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AI-extracted from the abstract
Characteristics Commentary
Topics Depression Psilocybin
Key points Argues that evidence for psilocybin in chronic depression is limited and primarily based on treatment-resistant cases, and that while promising results exist, more targeted and extensive research is needed.

Abstract

Evidence for psilocybin use in chronic depression is limited, primarily focusing on treatment-resistant cases. While promising results have been noted in studies, more targeted and extensive research is needed.

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