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Altered consciousness in flotation-REST and chamber-REST: Experience of experimental pain and subjective stress

Anette Kjellgren, U. Sundequist, Ulla Sundholm, Torsten Norlander, T. Archer

January 3, 2004 DOI: 10.2224/sbp.2004.32.2.103 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized crossover trial
Sample size 23
Population Sportsmen
Interventions Flotation-REST Chamber-REST
Duration Two 45-minute sessions
Measures instrument assessing experienced deviation from normal state (EDN)
Topics Altered states of consciousness
Key findings Flotation-REST induced significantly higher altered states of consciousness than chamber-REST. Participants with high altered states in the flotation condition reported greater experienced pain and stress than those with low altered states, suggesting flotation-REST may influence pain and stress perception.

Abstract

Twenty-three sportsmen were given one 45-minute exposure to flotation-REST and one exposure to chamber-REST on two occasions, incorporating random assignment to either flotation-REST followed by chamber-REST or vice versa. On each occasion, the Restricted Environmental Stimulation Technique (REST) procedure was followed immediately by testing experimentally induced pain to one arm using a blood pressure cuff. It was found that flotation-REST induced a significantly higher degree of altered states of consciousness (ASC), as measured with an instrument assessing experienced deviation from normal state (EDN), than did chamber-REST. Participants experiencing High EDN in the flotation-REST condition reported higher levels of both “experienced pain” and “experienced stress” than did those experiencing Low EDN. These results suggest that the particular distinguishing features of flotation-REST and chamber-REST may cause selective deviations from normal levels of consciousness, under experimental conditions, that may underlie the subjective experience of pain and stress thresholds.

Comparable studies

Other randomized controlled trials on altered states of consciousness, most cited first.

Study Year Design Participants
Changes in global and thalamic brain connectivity in LSD-induced altered states of consciousness are attributable to the 5-HT2A receptor Healthy human participants 2018 Double-blind, randomized, counterbalanced, cross-over study n = 24
Effective connectivity changes in LSD-induced altered states of consciousness in humans. Healthy participants 2019 Double-blind, randomized, placebo-controlled, cross-over study n = 25
Dose-related effects of salvinorin A in humans: dissociative, hallucinogenic, and memory effects. Healthy hallucinogen-using adults 2013 Double-blind, placebo-controlled study n = 8
High doses of dextromethorphan, an NMDA antagonist, produce effects similar to classic hallucinogens. Healthy volunteers with histories of hallucinogen use 2012 Randomized controlled trial n = 12
A placebo-controlled investigation of synaesthesia-like experiences under LSD. 2016 Within-groups placebo-controlled pilot study

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