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The neural substrates of mindfulness: an fMRI investigation.

Social Neuroscience September 9, 2010 DOI: 10.1080/17470919.2010.513495 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational cohort Peer reviewed
Topics Meditation
Key findings Proposes that mindfulness practice is associated with increased prefrontal activation and decreased amygdala activation, suggesting enhanced top-down emotional regulation.

Abstract

The neural substrates of mindfulness: an fMRI investigation.

Comparable studies

Other observational and cohort studies on meditation, most cited first.

Study Year Design Participants
Using Self-Report Assessment Methods to Explore Facets of Mindfulness Undergraduate students 2006 Observational cohort
Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders Patients with generalized anxiety disorder or panic disorder with or without agoraphobia 1992 Observational cohort n = 22
Meditation experience is associated with increased cortical thickness Participants with extensive Insight meditation experience and matched controls 2005 Observational cohort n = 20
Meditation experience is associated with differences in default mode network activity and connectivity Experienced meditators and matched meditation-naive controls 2011 Observational cohort
Long-term meditators self-induce high-amplitude gamma synchrony during mental practice Long-term Buddhist practitioners and controls 2004 Observational cohort

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