Effects of mindfulness based stress reduction program on depression, anxiety and stress in patients with aneurysmal subarachnoid hemorrhage.
Hye Myung Joo, Sung Jae Lee, Yong Gu Chung, Il Young Shin
Journal of Korean Neurosurgical Society May 2010 DOI: 10.3340/jkns.2010.47.5.345 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Sample size | 11 |
| Population | Patients with depression and anxiety symptoms after surgery for spontaneous subarachnoid hemorrhage |
| Intervention | Mindfulness Based Stress Reduction (MBSR) |
| Duration | 8-week intervention |
| Measures | Beck Depression Inventory (BDI), State-Trait Anxiety Inventory, Heart Rate Variability (HRV), Physical Stress Index (PSI) |
| Topics | Anxiety Depression Meditation |
| Keywords | Depression anxiety Subarachnoid hemorrhage |
| Key findings | MBSR significantly reduced depression scores (BDI from 18.5 to 9.5, p=0.013) and improved heart rate variability measures, while anxiety reductions were not statistically significant. The authors propose MBSR as a potential tool to improve quality of life after SAH surgery. |
Abstract
In this study, the Mindfulness Based Stress Reduction (MBSR) program was applied to patients presenting with depression and anxiety after surgery from spontaneous subarachnoid hemorrhage (SAH) and the effects were assessed. The subjects were patients admitted for cerebral aneurysm rupture and treated by means of surgery from March to December, 2007. More than 6 months had passed after surgery, without any special lesions showing up on computed tomography (CT), and the Glasgow outcome scale (GOS) was 5 points. Among patients with anxiety and depression symptoms, 11 patients completed the program. The MBSR program was conducted once a week, 2.5 hours each, for 8 weeks. The evaluation criteria were : 1) the Beck Depression Inventory (BDI): it measures the type and level of depression, 2) the State-Trait Anxiety Inventory : the anxiety state of normal adults without mental disorder, and 3) Heart Rate Variability (HRV) : the influence of the autonomous nervous system on the sinoarterial node varies continuously in response to the change of the internal/external environment. The BDI value was decreased from 18.5 +/- 10.9 to 9.5 +/- 7.1 (p = 0.013) : it was statistically significant, and the depression level of patients was lowered. The state anxiety was decreased from 51.3 +/- 13.9 to 42.3 +/- 15.2; the trait anxiety was reduced from 50.9 +/- 12.3 to 41.3 +/- 12.8, and a borderline significant difference was shown (p = 0.091, p = 0.056). In other words, after the treatment, although it was not statistically significant, a decreased tendency in anxiety was shown. In the HRV measurement, standard deviation normal to normal (SDNN), square root of the square root of the mean sum of squared differences between adjacent normal to normal intervals (RMSSD), and total power (TP) showed significant increase, Physical Stress Index (PSI) showed a significant reduction, and thus an improvement in the homeostatic control mechanism of the autonomic nervous system was ween. The MBSR program was applied to the patients showing anxiety and depression reaction after SAH treatment, and a reduction in depression symptoms and physiological reactions were observed. The application of the MBSR program may be considered as a new tool in improving the quality of life for patients after surgery.
Comparable studies
Other observational and cohort studies on anxiety, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders Patients with generalized anxiety disorder or panic disorder with or without agoraphobia | 1992 | Observational cohort | n = 22 |
| Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report Patients with a depressive disorder | 2015 | Observational study | |
| Patterning of Cognitive and Somatic Processes in the Self-Regulation of Anxiety: Effects of Meditation versus Exercise Regular practitioners of physical exercise or meditation | 1978 | Retrospective study | n = 77 |
| Dynamic coupling of whole-brain neuronal and neurotransmitter systems Healthy humans | 2020 | Observational study | |
| Psychedelics not linked to mental health problems or suicidal behavior: A population study Randomly selected United States adults | 2015 | Observational cohort | n = 135,095 |
Citations in the library
Cited by 19
- Mindfulness-Based Stress Reduction, Mindfulness-Based Cognitive Therapy, and Zen Meditation for Depression, Anxiety, Pain, and Psychological Distress Journal of Psychiatric Practice July 1, 2012
- Mindfulness-Based Interventions for Physical Conditions: A Narrative Review Evaluating Levels of Evidence ISRN Psychiatry November 14, 2012
- Self-Referential Thinking, Suicide, and Function of the Cortical Midline Structures and Striatum in Mood Disorders: Possible Implications for Treatment Studies of Mindfulness-Based Interventions for Bipolar Depression Depression Research and Treatment 2012
- A new mindfulness and psycho-educative program for treatment of brain fatigue, evaluated after an acquired brain injury and multiple sclerosis. Health psychology and behavioral medicine 2025
- Correlation Status of Mindfulness with Depression, Anxiety, and Related Factors in Students of Khalkhal Faculty of Medical Sciences Journal of Health and Hygiene October 1, 2024
and 14 more in the library
Cites 10
- Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders American Journal of Psychiatry July 1, 1992
- A Randomized, Wait-List Controlled Clinical Trial: The Effect of a Mindfulness Meditation-Based Stress Reduction Program on Mood and Symptoms of Stress in Cancer Outpatients Psychosomatic Medicine September 1, 2000
- Mindfulness-Based Stress Reduction in Relation to Quality of Life, Mood, Symptoms of Stress, and Immune Parameters in Breast and Prostate Cancer Outpatients Psychosomatic Medicine July 1, 2003
- An Exploratory Study of a Meditation-based Intervention for Binge Eating Disorder Journal of Health Psychology May 1, 1999
- Mindfulness meditation alleviates depressive symptoms in women with fibromyalgia: Results of a randomized clinical trial Arthritis Care & Research January 31, 2007
and 5 more in the library