Longitudinal impact of mindfulness meditation on illness burden in solid-organ transplant recipients.
Mary Jo Kreitzer, Cynthia R Gross, Xin Ye, Valerie Russas, Charoen Treesak
Progress in transplantation June 2005 DOI: 10.1177/152692480501500210 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Clinical trial Longitudinal Peer reviewed |
|---|---|
| Sample size | 20 |
| Population | Solid-organ transplant recipients |
| Intervention | Mindfulness-based stress reduction |
| Duration | 8-week course, 6-month follow-up |
| Topics | Meditation |
| Key findings | Mindfulness-based stress reduction significantly improved sleep quality and duration, with gains persisting six months post-course; self-reported anxiety and depression also improved. |
Abstract
In 2001, more than 24000 solid-organ transplant surgeries were performed in the United States. Although survival rates have steadily risen over the past 2 decades, transplant recipients commonly experience a myriad of symptoms after transplantation that compromise quality of life. Anxiety, depression, and insomnia frequently occur despite excellent function of the transplanted organ. Use of complementary and alternative medicine has risen sharply over the past 10 years, particularly among people with chronic illnesses. Twenty solid-organ transplant recipients were enrolled in a clinical trial of mindfulness-based stress reduction. During the 8-week course, subjects learned various forms of meditation and gentle hatha yoga. Participants were given audiotapes for home practice and maintained practice diaries. Longitudinal analysis focused on the impact of mindfulness-based stress reduction on symptom management, illness intrusion, and transplant-related stressors. Significant improvements in the quality and duration of sleep continued for 6 months after completion of the mindfulness-based stress reduction course. Improvements after the completion of the course were also noted in self-report measures of anxiety and depression. Mindfulness-based stress reduction is an effective treatment in improving the quality and duration of sleep. Because sleep is highly correlated with positive mental health and overall well-being, these findings suggest that mindfulness-based stress reduction has the potential of being an effective, accessible and low-cost intervention that could significantly change transplant recipients' overall health and well-being.
Comparable studies
Other non-randomized and open-label trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Mindfulness-Based Stress Reduction in Relation to Quality of Life, Mood, Symptoms of Stress, and Immune Parameters in Breast and Prostate Cancer Outpatients Early-stage breast and prostate cancer patients | 2003 | Pre-post intervention study | n = 59 |
| Exploring self‐compassion and empathy in the context of mindfulness‐based stress reduction (MBSR) Community sample | 2010 | Pre-post intervention study | |
| Mindfulness-Based Stress Reduction Lowers Psychological Distress In Medical Students Second-year medical students | 2003 | Prospective nonrandomized cohort-controlled study | n = 302 |
| Intensive meditation training, immune cell telomerase activity, and psychological mediators. Retreat participants and matched controls | 2011 | Controlled trial with wait-list control group | n = 60 |
| The Effectiveness of Mindfulness Training for Children with ADHD and Mindful Parenting for their Parents Children aged 8-12 with ADHD and their parents | 2011 | Within-group waitlist controlled trial | n = 22 |
Citations in the library
Cited by 23
- A systematic review of neurobiological and clinical features of mindfulness meditations Psychological Medicine November 27, 2009
- Effect of Mindfulness‐Based stress reduction in rheumatoid arthritis patients Arthritis Care & Research September 28, 2007
- Prospects for a clinical science of mindfulness-based intervention. American Psychologist October 1, 2015
- Mindfulness-Based Interventions for Physical Conditions: A Narrative Review Evaluating Levels of Evidence ISRN Psychiatry November 14, 2012
- P02-335 - A Systematic Review of Neurobiological and Clinical Features of Mindfulness Meditations European Psychiatry 2010
and 18 more in the library
Cites 6
- Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Journal of Consulting and Clinical Psychology 2000
- A Randomized, Wait-List Controlled Clinical Trial: The Effect of a Mindfulness Meditation-Based Stress Reduction Program on Mood and Symptoms of Stress in Cancer Outpatients Psychosomatic Medicine September 1, 2000
- Mindfulness-based stress reduction and health-related quality of life in a heterogeneous patient population. General Hospital Psychiatry July 1, 2001
- The effects of a mindfulness meditation-based stress reduction program on mood and symptoms of stress in cancer outpatients: 6-month follow-up. Supportive Care in Cancer March 2001
- Influence of a mindfulness meditation-based stress reduction intervention on rates of skin clearing in patients with moderate to severe psoriasis undergoing phototherapy (UVB) and photochemotherapy (PUVA). Psychosomatic Medicine 1998
and 1 more in the library