Does cannabidiol protect against the negative effects of THC?

The British Journal of Psychiatry September 30, 2010 DOI: 10.1192/bjp.bp.110.081380 (opens in new tab)

Study at a glance

AI-extracted from the abstract

Characteristics	News report Peer reviewed
Topics	Cannabis CBD
Citations	16
Key points	Reports that CBD attenuates the acute cognitive effects of THC, suggesting a potential protective role in reducing THC-related harms.

Abstract

A recent study by Morgan and colleagues found that cannabidiol attenuates the acute cognitive effects of delta-9-tetrahydrocannabinol (THC). This is of interest as THC has been associated with the detrimental effects of cannabis on mental health in at-risk users, and the potency of cannabis is increasing across Europe.

Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study: naturalistic study [corrected]. The British journal of psychiatry : the journal of mental science October 2010
Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment Journal of Psychopharmacology October 5, 2012 463 citations
Cannabidiol Increases Psychotropic Effects and Plasma Concentrations of Δ9-Tetrahydrocannabinol Without Improving Its Analgesic Properties. Clinical pharmacology and therapeutics November 1, 2024 17 citations
Does Cannabis Composition Matter? Differential Effects of Delta-9-tetrahydrocannabinol and Cannabidiol on Human Cognition Current Addiction Report April 29, 2017
Opposite Roles for Cannabidiol and δ-9-Tetrahydrocannabinol in Psychotomimetic Effects of Cannabis Extracts Journal of Clinical Psychopharmacology August 20, 2021 17 citations

Study at a glance

Abstract

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