Microdosing: Concept, Application and Relevance
Perspectives in Clinical Research April 1, 2010 DOI: 10.4103/2229-3485.71853 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Commentary Peer reviewed |
|---|---|
| Topics | Microdosing |
| Keywords | Law |
| Key points | Argues that India's lack of enabling regulations for microdosing studies hinders its pharmaceutical research ambitions, whereas Europe and the USA have benefited from clear regulatory frameworks. |
Abstract
The use of microdose pharmacokinetic studies as an essential tool in drug development is still to catch on. While this approach promises potential cost savings and a quantum leap in efficiencies of the drug development process, major hurdles still need to be overcome before the technique becomes commonplace and part of routine practice. Clear regulations in Europe and the USA have had an enabling effect. The lack of enabling provisions for microdosing studies in Indian regulation, despite low risk and manifest relevance for the local drug development industry, is inconsistent with the country's aspirations to be among the leaders in pharmaceutical research.