Enhanced hippocampal long-term potentiation following repeated MDMA treatment in Dark-Agouti rats.
European Neuropsychopharmacology August 19, 2010 DOI: 10.1016/j.euroneuro.2010.07.007 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Experimental study Peer reviewed |
|---|---|
| Population | Dark-Agouti rats |
| Topics | MDMA |
| Key findings | Repeated MDMA treatment increased hippocampal long-term potentiation in Dark-Agouti rats, suggesting enhanced synaptic plasticity. |
Abstract
Enhanced hippocampal long-term potentiation following repeated MDMA treatment in Dark-Agouti rats.
Comparable studies
Other preclinical and animal studies on MDMA, most cited first.
Citations in the library
Cited by 7
- Pharmacokinetics and pharmacodynamics of 3,4-methylenedioxymethamphetamine (MDMA): interindividual differences due to polymorphisms and drug–drug interactions Critical Reviews in Toxicology October 3, 2012
- Aromatic Bromination Abolishes Deficits in Visuospatial Learning Induced by MDMA (“Ecstasy”) in Rats While Preserving the Ability to Increase LTP in the Prefrontal Cortex International Journal of Molecular Sciences February 13, 2023
- Cognitive dysfunction and impaired neuroplasticity following repeated exposure to the synthetic cannabinoid JWH-018 in male mice. British Journal of Pharmacology July 13, 2023
- Downregulation of the Vitamin D Receptor Regulated Gene Set in the Hippocampus After MDMA Treatment. Frontiers in Pharmacology 2018
- Treadmill exercise alters ecstasy- induced long- term potentiation disruption in the hippocampus of male rats. Metabolic Brain Disease October 2017
and 2 more in the library
Cites 18
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- Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity Journal of Neuroscience August 1, 1988
- 3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites. Journal of Pharmacology and Experimental Therapeutics September 1, 1987
- Altered Serotonin Innervation Patterns in the Forebrain of Monkeys Treated with (±)3,4-Methylenedioxymethamphetamine Seven Years Previously: Factors Influencing Abnormal Recovery Journal of Neuroscience June 15, 1999
- (±3,4-Methylenedioxymethamphetamine Selectively Damages Central Serotonergic Neurons in Nonhuman Primates JAMA July 1, 1988
and 13 more in the library