Acute concomitant effects of MDMA binge dosing on extracellular 5-HT, locomotion and body temperature and the long-term effect on novel object discrimination in rats.
Psychopharmacology (Berl) July 20, 2010 DOI: 10.1007/s00213-010-1921-9 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational study Peer reviewed |
|---|---|
| Population | Rats |
| Intervention | MDMA |
| Measures | novel object discrimination |
| Topics | MDMA |
| Key findings | Binge MDMA dosing acutely increased extracellular 5-HT, locomotion, and body temperature, and impaired novel object discrimination in the long term, indicating lasting cognitive deficits. |
Abstract
Acute concomitant effects of MDMA binge dosing on extracellular 5-HT, locomotion and body temperature and the long-term effect on novel object discrimination in rats.