Skip to content

Acute and Long-Term Behavioural Effects of MDMA in Adolescent Rats

Esther Remmelink

The Open Addiction Journal March 29, 2011 DOI: 10.2174/1874941001104010042 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Experimental study (animal study) Peer reviewed
Population Adolescent rats
Intervention MDMA
Topics MDMA
Key findings The abstract states the study's objectives but does not report any findings or conclusions. It indicates that the research investigates whether MDMA's effects in adult rats—acute increases in social interaction and long-term decreases in social interaction, increased anxiety, and impaired object recognition memory—also occur in adolescent rats, and whether social context mediates adolescent preference for MDMA.

Abstract

Acute MDMA, even at low doses, increases social interaction in adult rats [1] while on the long-term its consumption produces a decrease in social interaction, an increase in anxiety and impaired object recognition memory [2, 3]. This study investigated whether MDMA has the same effects in adolescent rats. Additionally, we investigated whether the preference of adolescent rats for MDMA was mediated by social context.