Comparative neurochemical profile of 3,4-methylenedioxymethamphetamine and its metabolite alpha-methyldopamine on key targets of MDMA neurotoxicity.
Neurochemistry International November 11, 2010 DOI: 10.1016/j.neuint.2010.11.001 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Comparative study Peer reviewed |
|---|---|
| Topics | MDMA |
| Key points | Argues that alpha-methyldopamine, a metabolite of MDMA, exhibits a distinct neurochemical profile on key targets of MDMA neurotoxicity, suggesting it contributes to the neurotoxic effects of MDMA. |
Abstract
Comparative neurochemical profile of 3,4-methylenedioxymethamphetamine and its metabolite alpha-methyldopamine on key targets of MDMA neurotoxicity.
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- Protective effects of physical exercise on MDMA-induced cognitive and mitochondrial impairment. Free radical biology & medicine October 2016
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Cites 20
- Human Pharmacology of MDMA Therapeutic Drug Monitoring March 19, 2004
- Carrier‐Mediated Release of Serotonin by 3,4‐Methylenedioxymethamphetamine: Implications for Serotonin‐Dopamine Interactions Journal of Neurochemistry 1996
- Pharmacology of MDMA in Humans Annals of the New York Academy of Sciences September 1, 2000
- The hyperthermic and neurotoxic effects of ‘Ecstasy’ (MDMA) and 3,4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotype British Journal of Pharmacology August 1, 1995
- MDMA (Ecstasy) and the Rave: A Review Pediatrics October 1, 1997
and 15 more in the library