Gender differences in hyperthermia and regional 5-HT and 5-HIAA depletion in the brain following MDMA administration in rats.
Brain Res May 4, 2011 DOI: 10.1016/j.brainres.2011.04.039 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Experimental study Peer reviewed |
|---|---|
| Population | Rats |
| Intervention | MDMA |
| Topics | MDMA |
| Key findings | Female rats exhibited greater hyperthermia and more extensive depletion of 5-HT and 5-HIAA in brain regions following MDMA administration compared to male rats, indicating sex-dependent neurochemical and physiological responses. |
Abstract
Gender differences in hyperthermia and regional 5-HT and 5-HIAA depletion in the brain following MDMA administration in rats.