Skip to content

Effect of Mindfulness-Based Stress Reduction with 40 Hz Music on Anxiety and Quality of Life in Prolanis Patients with Diabetes Mellitus

Muhammad Akbar Sobarna, Fery Agusman, Motuho Mendrofa, D. I. Iswanti

Journal of Nursing and Practice April 6, 2026 DOI: 10.30994/jnp.v9i3.1089 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Quasi-experimental pretest-posttest control group Peer reviewed
Sample size 60
Population Prolanis patients with Diabetes Mellitus
Interventions Mindfulness-Based Stress Reduction 40 Hz music frequency
Duration 8-week intervention
Measures DASS-21, WHOQOL-BREF
Topics Anxiety Meditation
Key findings MBSR combined with 40 Hz music frequency significantly reduced anxiety (mean difference = -10.15) and improved quality of life (median increase = +16) in the intervention group, while the control group showed no significant changes.

Abstract

Background: Anxiety is a common psychological problem experienced by patients with Diabetes Mellitus and can negatively affect disease management and quality of life. Mindfulness-Based Stress Reduction (MBSR) combined with 40 Hz music frequency is that may help reduce anxiety and improve quality of life in patients with chronic diseases.

Purpose: This study aimed to analyze the effectiveness of MBSR with 40 Hz music frequency on anxiety and quality of life among Prolanis patients with Diabetes Mellitus.

Methods: Study design used a quasi-experimental pretest–posttest control group. The sample consisted of 60 respondents, divided into intervention and control groups. The intervention group received an 8-week MBSR program combined with 40 Hz music frequency, while the control group received standard Prolanis care. Anxiety levels using the DASS-21 questionnaire, and quality of life was assessed using WHOQOL-BREF. Data were analyzed using Wilcoxon and Mann–Whitney tests.

Results: The anxiety levels significantly decreased in the intervention group (mean difference = −10.15; p < 0.001), while no significant change was observed in the control group (p > 0.05). In addition, quality of life significantly improved in the intervention group (median increase = +16; p < 0.001), whereas the control group showed only a slight and non-significant improvement (p > 0.05).

Conclusion: Mindfulness-Based Stress Reduction combined with 40 Hz music frequency is effective in reducing anxiety and improving quality of life among Prolanis patients with Diabetes Mellitus. This intervention can be integrated into primary healthcare services as a complementary nursing intervention to support holistic diabetes management.

Comparable studies

Other experimental studies on anxiety, most cited first.

Study Year Design Participants
A PILOT STUDY OF GROUP MINDFULNESS-BASED COGNITIVE THERAPY (MBCT) FOR COMBAT VETERANS WITH POSTTRAUMATIC STRESS DISORDER (PTSD) Veterans with chronic combat posttraumatic stress disorder seeking treatment at a VA... 2013 Quasi-experimental with treatment-as-usual comparison group n = 37
Being present in the face of existential threat: The role of trait mindfulness in reducing defensive responses to mortality salience. 2010 Experimental study
Neural correlates of mindfulness meditation-related anxiety relief Healthy adults with no prior meditation experience 2013 Within-subjects experimental study n = 15
Intensive mindfulness training-related changes in cognitive and emotional experience Community adults 2009 Quasi-experimental and longitudinal n = 69
Prospective examination of synthetic 5-methoxy-N,N-dimethyltryptamine inhalation: effects on salivary IL-6, cortisol levels, affect, and non-judgment Volunteers 2019 Within-subjects experimental study n = 11

Explore topics