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Effect of a 5-Minute Mindfulness-of-Gratitude Practice on Suffering and Spiritual Well-Being in Palliative Care Inpatients: A Randomized Controlled Study.

The American journal of hospice & palliative care July 22, 2026 DOI: 10.1177/10499091261471078 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial Peer reviewed
Population Palliative care inpatients
Intervention Mindfulness-of-gratitude practice
Dose 5-minute session
Topics End-of-life distress Meditation
Key findings The 5-minute mindfulness-of-gratitude practice significantly reduced suffering and improved spiritual well-being in palliative care inpatients compared to the control group, indicating its potential as a brief intervention for existential distress.

Abstract

Effect of a 5-Minute Mindfulness-of-Gratitude Practice on Suffering and Spiritual Well-Being in Palliative Care Inpatients: A Randomized Controlled Study.

Comparable studies

Other randomized controlled trials on end-of-life distress, most cited first.

Study Year Design Participants
Acute and Sustained Reductions in Loss of Meaning and Suicidal Ideation Following Psilocybin-Assisted Psychotherapy for Psychiatric and Existential Distress in Life-Threatening Cancer People with advanced cancer 2021 Randomized controlled trial
PAM trial protocol: a randomised feasibility study of psychedelic microdosing-assisted meaning-centred psychotherapy in advanced stage cancer patients. Māori and non-Māori adults with advanced-stage cancer and symptoms of anxiety and/or... 2024 Randomized controlled trial protocol n = 40
Integrating Immersive Virtual Reality Meditation into Palliative Oncology: A Randomized Trial Protocol for Evaluating Pain Relief and Quality of Life Cancer patients under palliative care at the Pain Therapy and Palliative Care Service... 2026 Randomized clinical trial
The effectiveness of reminiscence therapy on the symptom management, the life satisfaction, and the self-transcendence in palliative care patients: a randomized controlled trial. Palliative care patients without cognitive impairment and able to communicate 2024 Randomized controlled trial n = 44

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