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Role of β-Arrestin2 Signaling in Neuropharmacological Effects of Psychedelic Drugs.

ACS Chem Neurosci August 1, 2026 DOI: 10.1021/acschemneuro.6c00138 (opens in new tab)

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Characteristics	Theoretical or philosophical paper Peer reviewed
Key points	Argues that β-arrestin2 signaling is a critical mediator of psychedelic drug effects, potentially explaining their therapeutic benefits and guiding drug development.

Abstract

Role of β-Arrestin2 Signaling in Neuropharmacological Effects of Psychedelic Drugs.

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