The impact of fluoxetine on the aversive effects of lysergic acid diethylamide.
Experimental and Clinical Psychopharmacology August 10, 2026 DOI: 10.1037/pha0000876 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Population | Healthy volunteers |
| Interventions | Fluoxetine Lysergic acid diethylamide |
| Topics | LSD |
| Key findings | Fluoxetine pretreatment reduced the aversive subjective effects of LSD, including anxiety and dysphoria, in healthy volunteers. |
Abstract
The impact of fluoxetine on the aversive effects of lysergic acid diethylamide.
Comparable studies
Other observational and cohort studies on LSD, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Increased Global Functional Connectivity Correlates with LSD-Induced Ego Dissolution. Human participants | 2016 | Observational cohort | |
| Increased spontaneous MEG signal diversity for psychoactive doses of ketamine, LSD and psilocybin Humans | 2017 | Observational study | |
| Classic psychedelic use is associated with reduced psychological distress and suicidality in the United States adult population. USA adult respondents from the National Survey on Drug Use and Health (2008-2012) | 2015 | Observational cohort | n = 190,000 |
| Psychedelics not linked to mental health problems or suicidal behavior: A population study Randomly selected United States adults | 2015 | Observational cohort | n = 135,095 |
| Whole-Brain Multimodal Neuroimaging Model Using Serotonin Receptor Maps Explains Non-linear Functional Effects of LSD. Healthy human participants | 2018 | Observational study with computational modeling |