LSD therapy: A few hundred meters from where it began.
Felix Müller, Anna M Becker, Christopher Böhlke, Matthias E. Liechti, Undine E. Lang
Med (New York, N.Y.) August 14, 2026 DOI: 10.1016/j.medj.2026.101233 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized trial Peer reviewed |
|---|---|
| Population | Patients with major depression |
| Intervention | LSD-assisted therapy |
| Topics | LSD |
| Key findings | The text does not report specific findings; it reflects on the experience of conducting the trial and highlights what remains uncertain about LSD-assisted therapy for major depression. |
Abstract
In Basel, only a few hundred meters from where LSD was first synthesized, we tested LSD-assisted therapy for major depression in a randomized trial comparing two high doses with two low doses, each paired with supportive psychotherapy. This Backstory reflects on treating patients, long dosing days, and what remains uncertain.