Stopping cannabis use benefits outcome in psychosis: findings from 10‐year follow‐up study in the PAFIP‐cohort
E. Setién-Suero, Karl Neergaard, V. Ortiz-García de la Foz, P. Suárez-Pinilla, O. Martínez‐García, B. Crespo-Facorro, R. Ayesa‐Arriola
Acta Psychiatrica Scandinavica August 5, 2019 DOI: 10.1111/acps.13081 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Population | Patients with first episode of psychosis (FEP) |
| Duration | Up to 10 years |
| Topics | Cannabis |
| Key findings | The study indicates that long-term cannabis use in patients with first-episode psychosis is associated with poorer clinical and functional outcomes over up to 10 years. The effect on neurocognition is not specified in the abstract. |
Abstract
To examine the long‐term (up to 10 years) patterns related to cannabis use in a sample of patients with first episode of psychosis (FEP) and the effect that consumption might have on clinical, functioning, and neurocognition at long‐term.
Comparable studies
Other observational and cohort studies on cannabis, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| High-potency cannabis and the risk of psychosis People with first episode of psychosis and healthy controls from the local population | 2009 | Case-control study | n = 454 |
| Ayahuasca-Assisted Therapy for Addiction: Results from a Preliminary Observational Study in Canada Rural aboriginal population | 2013 | Observational study | |
| Impaired cognitive performance in drug free users of recreational ecstasy (MDMA) Otherwise healthy young people | 2000 | Observational | |
| Continued cannabis use and risk of incidence and persistence of psychotic symptoms: 10 year follow-up cohort study Individuals from the general population in Germany aged 14-24 at baseline | 2011 | Observational cohort | n = 1,923 |
| Cannabis-induced psychosis and subsequent schizophrenia-spectrum disorders: follow-up study of 535 incident cases Patients treated for cannabis-induced psychotic symptoms in Denmark between 1994 and... | 2005 | Observational cohort | n = 535 |
Citations in the library
Cited by 6
- From heavy cannabis use to psychosis: is it time to take action? Irish Journal of Psychological Medicine May 27, 2021
- Cannabis Use and Psychosis – Modern Views on the Problem. Narrative Synthesis Medicina 2021
- Insight into cannabis use disorder in people with psychotic disorders BJPsych Open August 25, 2026
- Cannabis Use Interacts With Psychosis Vulnerability in Borderline Personality Disorder: La consommation de cannabis interagit avec la vulnérabilité à la psychose dans le trouble de la personnalité limite The Canadian Journal of Psychiatry September 11, 2026
- Cannabis and Psychosis. Child and Adolescent Psychiatric Clinics of North America October 1, 2022
and 1 more in the library
Cites 8
- Causal association between cannabis and psychosis: examination of the evidence The British Journal of Psychiatry January 30, 2004
- Course of cannabis use and clinical outcome in patients with non-affective psychosis: a 3-year follow-up study Psychological Medicine February 5, 2015
- The contribution of cannabis use to variation in the incidence of psychotic disorder across Europe (EU-GEI): a multicentre case-control study The Lancet Psychiatry May 1, 2019
- Cannabis use in male and female first episode of non-affective psychosis patients: Long-term clinical, neuropsychological and functional differences PLoS One August 23, 2017
- Continued versus discontinued cannabis use in patients with psychosis: a systematic review and meta-analysis. The Lancet Psychiatry March 1, 2016
and 3 more in the library