Distress tolerance as a mechanism of mindfulness for depression and anxiety: Cross-sectional and diary evidence
Yanjuan Li, Ruilin Ju, Stefan G Hofmann, Wingsze Chiu, Ye Guan, Yu Leng, Xinghua Liu
International Journal of Clinical and Health Psychology July 5, 2023 DOI: 10.1016/j.ijchp.2023.100392 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Cross-sectional study; daily diary study Peer reviewed |
|---|---|
| Sample size | 1,015 |
| Population | Adults (Study 1: n=905; Study 2: n=110) |
| Duration | 14 consecutive days for the daily diary study |
| Topics | Anxiety Depression Meditation |
| Key findings | Distress tolerance mediated the relationship between mindfulness and depression/anxiety at both between-person and within-person levels. |
Abstract
Background: Both trait and state mindfulness are associated with less depression and anxiety, but the mechanisms remain unknown. Distress tolerance, an important transdiagnostic factor of emotional disorders, may mediate the relationship between mindfulness and depression/anxiety.
Method: Study 1 examined the mediation model at the between-person level in a large cross-sectional sample (n = 905). In Study 2, a daily diary study (n = 110) was conducted to examine within-person changes. Participants were invited to complete daily diaries measuring daily mindfulness, distress tolerance, depression and anxiety for 14 consecutive days.
Results: In Study 1, results of simple mediation analyses indicated that distress tolerance mediated the relationship between mindfulness and depression/anxiety at the between-person level. In Study 2, results of multilevel mediation analyses indicated that, in both the concurrent model and time-lagged model, daily distress tolerance mediated the effects of daily mindfulness on daily depression/anxiety at both the within- and between-person level.
Conclusions: Distress tolerance is a mechanism underlying the relationship between mindfulness and depression/anxiety. Individuals with high or fluctuating depression and anxiety may benefit from short-term or long-term mindfulness training to increase distress tolerance.
Comparable studies
Other cross-sectional and survey studies on anxiety, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Psychological flexibility mediates the relations between acute psychedelic effects and subjective decreases in depression and anxiety. International sample of people who reported having used a psychedelic | 2020 | Cross-sectional survey | n = 985 |
| The Challenging Experience Questionnaire: Characterization of challenging experiences with psilocybin mushrooms Internet survey respondents reporting challenging experiences with psilocybin | 2016 | Questionnaire development and validation | |
| Psychedelics and Mental Health: A Population Study Adult population in the United States | 2013 | Cross-sectional survey | n = 130,152 |
| Ecstasy/MDMA attributed problems reported by novice, moderate and heavy recreational users Ecstasy users who participated in a WWW study of recreational drug use | 2002 | Cross-sectional survey | n = 282 |
| 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) used in a naturalistic group setting is associated with unintended improvements in depression and anxiety. Adults who used 5-MeO-DMT in a group setting with structured procedures | 2019 | Cross-sectional survey | n = 362 |
Citations in the library
Cited by 7
- Distress tolerance as a mediator of mindfulness-based intervention for anxiety and depression: Evidence from two randomized controlled trials. International journal of clinical and health psychology : IJCHP 2024
- Feasibility and effects of mindfulness-based stress reduction (MBSR) for improving resilience, posttraumatic stress disorder symptoms and posttraumatic growth among military medical college students. Acta Psychologica November 1, 2024
- Rumination and Self-Compassion Moderate Mindfulness-Based Cognitive Therapy for Patients With Recurrent and Persistent Major Depressive Disorder: A Controlled Trial. Depression and Anxiety 2024
- Mindfulness and trauma recovery among internally displaced individuals: the mediating role of distress tolerance in a cross-sectional mediation model Frontiers in Psychology September 24, 2025
- Temporal Precedence of Distress Tolerance in Predicting Anxiety and Depression: A Daily Diary Approach During Mindfulness-Based Intervention. Behavior Therapy May 1, 2026
and 2 more in the library
Cites 10
- Using Self-Report Assessment Methods to Explore Facets of Mindfulness Assessment January 27, 2006
- Mindfulness: A proposed operational definition. Clinical Psychology Science and Practice 2004
- Mindfulness training as a clinical intervention: A conceptual and empirical review. Clinical Psychology Science and Practice 2003
- Mechanisms of mindfulness Journal of Clinical Psychology December 29, 2005
- Mindfulness: Theoretical Foundations and Evidence for its Salutary Effects Psychological Inquiry October 19, 2007
and 5 more in the library