Disrupting the downward spiral of chronic pain and opioid addiction with mindfulness-oriented recovery enhancement: a review of clinical outcomes and neurocognitive targets.
Journal of Pain & Palliative Care Pharmacotherapy May 20, 2014 DOI: 10.3109/15360288.2014.911791 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Theoretical or philosophical paper Peer reviewed |
|---|---|
| Intervention | Mindfulness-Oriented Recovery Enhancement (MORE) |
| Topics | Addiction Meditation |
| Keywords | Humans Opioid-related disorders Analgesics, opioid Chronic pain Prescription drug misuse Cognitive behavioral therapy Pharmacotherapy Neurocognitive |
| Key points | Argues that Mindfulness-Oriented Recovery Enhancement (MORE), a behavioral treatment integrating mindfulness training, cognitive-behavioral therapy, and positive psychology, may target the risk chain linking chronic pain and prescription opioid misuse, and proposes that such nonpharmacologic interventions are needed to complement pharmacotherapy and interrupt behavioral escalation. |
Abstract
Prescription opioid misuse and addiction among chronic pain patients are problems of growing medical and social significance. Chronic pain patients often require intervention to improve their well-being and functioning, and yet, the most commonly available form of pharmacotherapy for chronic pain is centered on opioid analgesics--drugs that have high abuse liability. Consequently, health care and legal systems are often stymied in their attempts to intervene with individuals who suffer from both pain and addiction. As such, novel, nonpharmacologic interventions are needed to complement pharmacotherapy and interrupt the cycle of behavioral escalation. The purpose of this paper is to describe how the downward spiral of chronic pain and prescription opioid misuse may be targeted by one such intervention, Mindfulness-Oriented Recovery Enhancement (MORE), a new behavioral treatment that integrates elements from mindfulness training, cognitive-behavioral therapy, and positive psychology. The clinical outcomes and neurocognitive mechanisms of this intervention are reviewed with respect to their effects on the risk chain linking chronic pain and prescription opioid misuse. Future directions for clinical and pharmacologic research are discussed.
Comparable studies
Other theoretical and historical papers on addiction, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Psychedelics as Medicines: An Emerging New Paradigm General population | 2016 | Theoretical or philosophical paper | |
| Restructuring reward processing with Mindfulness-Oriented Recovery Enhancement: novel therapeutic mechanisms to remediate hedonic dysregulation in addiction, stress, and pain. | 2016 | Theoretical or philosophical paper | |
| Ayahuasca’s entwined efficacy: An ethnographic study of ritual healing from ‘addiction’ | 2017 | Theoretical or philosophical paper | |
| Hypotheses Regarding the Mechanisms of Ayahuasca in the Treatment of Addictions | 2012 | Theoretical or philosophical paper | |
| Biosynthesis of an Anti-Addiction Agent from the Iboga Plant. | 2019 | Theoretical or philosophical paper |
Citations in the library
Cited by 3
- The Effectiveness of a Mindfulness-Based Intervention Integrated with Physical Therapy (MIND-PT) for Postsurgical Rehabilitation After Lumbar Surgery: A Protocol for a Randomized Controlled Trial as Part of the Back Pain Consortium (BACPAC) Research Program. Pain Medicine August 1, 2023
- Mindfulness‐based cognitive therapy for chronic noncancer pain and prescription opioid use disorder: A qualitative pilot study of its feasibility and the perceived process of change Brain and Behavior May 24, 2023
- Mindfulness-Based Intervention Effects on Substance Use and Relapse Among Women in Residential Treatment: A Randomized Controlled Trial With 8.5-Month Follow-Up Period From the Moment-by-Moment in Women's Recovery Project. Psychosomatic Medicine July 1, 2021
Cites 11
- How Does Mindfulness Meditation Work? Proposing Mechanisms of Action From a Conceptual and Neural Perspective Perspectives on Psychological Science October 14, 2011
- Mindfulness-oriented recovery enhancement for chronic pain and prescription opioid misuse: results from an early-stage randomized controlled trial. Journal of Consulting and Clinical Psychology February 3, 2014
- Mindfulness-Oriented Recovery Enhancement Reduces Pain Attentional Bias in Chronic Pain Patients Psychotherapy and Psychosomatics 2013
- Mindfulness meditation-related pain relief: evidence for unique brain mechanisms in the regulation of pain. Neuroscience Letters April 6, 2012
- Brain mechanisms supporting the modulation of pain by mindfulness meditation. Journal of Neuroscience April 6, 2011
and 6 more in the library