Effectiveness of mindfulness-based stress reduction and mindfulness-based cognitive therapy on depression in poststroke patients-A systematic review and meta-analysis of randomized controlled trials.
Shiqi Tao, Yi Geng, Mingxia Li, Jing Ye, Zuoyan Liu
Journal of Psychosomatic Research October 1, 2022 DOI: 10.1016/j.jpsychores.2022.111071 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Systematic review and meta-analysis Randomized Peer reviewed |
|---|---|
| Sample size | 502 |
| Population | People who have experienced a stroke |
| Interventions | mindfulness-based stress reduction mindfulness-based cognitive therapy |
| Topics | Depression Meditation |
| Key findings | MBSR and MBCT significantly reduced depressive symptoms in poststroke participants, with a larger effect in those with clinically defined depression. |
Abstract
Objective: To evaluate the effectiveness of mindfulness-based stress reduction (MBSR) and mindfulness-based cognitive therapy (MBCT) on depressive symptoms in people with stroke.
Methods: The PubMed, CINAL, Web of Science, Embase, The Cochrane Library, CNKI, and Wangfang databases were searched for relevant articles from inception to September 1st, 2022. Only randomized controlled trials (RCTs) examining the effect of MBSR and MBCT on depressive symptoms in poststroke patients were included. Data extraction and critical appraisal were conducted independently by two investigators.
Results: Seven trials with 502 participants were included. Using standardized mean differences, the meta-analysis showed evidence of a significant effect in depression (SMD = -0.93, 95% CI (-1.34 to -0.53), Z = 4.48, p < 0.001). MBSR and MBCT both affected depressive emotions in poststroke participants with depression (SMD = -1.27, 95% CI (-1.71 to -0.84), p < 0.001) and poststroke participants without clinically defined depression (SMD = -0.46, 95% CI (-0.75 to -0.17), p = 0.002).
Conclusion: Although populations with stroke seem to potentially improve moods from MBSR/MBCT intervention, the impact on the physiological parameters of the disease has not been determined. Further studies with long-term follow-up and higher qualities are warranted for such interventions to determine the full effectiveness.
Comparable studies
Other systematic reviews and meta-analyses on depression, most cited first.
Citations in the library
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- Mindfulness- and acceptance-based interventions for people with spinal cord injury: a scoping review. Spinal cord March 1, 2025
- Online mindfulness-based cognitive therapy as an adjuvant-treatment for Chinese patients with psoriasis: A randomized controlled trial JAAD International February 20, 2026
- Enhancing psychological health and cognitive inhibition in college students: insights from mindfulness training and high-intensity interval training. Frontiers in Psychology 2025
- Solution-focused brief therapy combined with mindfulness-based cognitive therapy for post-stroke depression: a randomized controlled trial. Topics in stroke rehabilitation March 1, 2026
- Effectiveness of mindfulness-based stress reduction for depression in post-stroke patients: a systematic review and meta-analysis. Frontiers in Psychiatry 2026
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Cites 12
- Meditation experience is associated with increased cortical thickness Neuroreport November 7, 2005
- Meditation experience is associated with differences in default mode network activity and connectivity Proceedings of the National Academy of Sciences November 23, 2011
- Mindfulness-Based Cognitive Therapy for Depression: A New Approach to Preventing Relapse Psychotherapy Research March 1, 2003
- What Do We Really Know About Mindfulness-Based Stress Reduction? Psychosomatic Medicine 2002
- Mindfulness-based stress reduction (MBSR) improves long-term mental fatigue after stroke or traumatic brain injury Brain Injury July 13, 2012
and 7 more in the library