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Perspective Chapter: Mechanisms Underlying Complementary Therapies for Cognitive Enhancement

A. M. Roy, Sushil Prasad Mahato, Deepti Padmanabha Bhat, Subramanya Pailoor, Manickam Anjaladevi, Samiran Mondal

IntechOpen eBooks March 5, 2026 DOI: 10.5772/intechopen.1014004 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Review Longitudinal Peer reviewed
Interventions Meditation Yoga Tai Chi/Qigong Breathwork Music-based interventions
Topics Meditation
Keywords Cognition Modalities Modality human–computer interaction Leverage statistics Perspective graphical Neurocognitive Mhealth Cognitive psychology Connectomics
Key findings Mind-body therapies produce modest yet reliable improvements in attention, working memory, executive function, and cognitive flexibility across healthy and clinical populations.

Abstract

Cognitive enhancement is increasingly pursued through complementary mind–body therapies that target fundamental brain–body mechanisms. This chapter synthesizes evidence for core modalities such as meditation and yoga, and additional approaches including Tai Chi/Qigong, breathwork, and music-based interventions. Across healthy and clinical populations, these therapies produce modest yet reliable improvements in attention, working memory, executive function, and cognitive flexibility, while offering meaningful adjunctive benefits in neuropsychiatric and neurodegenerative conditions. Convergent mechanisms involve enhanced self-regulation, fronto-limbic and large-scale network plasticity, vagal predominance with greater heart-rate variability, normalization of Hypothalamic–Pituitary–Adrenal (HPA) axis activity, and anti-inflammatory immune modulation. Movement-based practices engage neurovascular and sensorimotor systems, breathwork supports baroreflex and neurovisceral coupling, and music-based approaches leverage dopaminergic reward and social engagement. Implementation requires standardized curricula (e.g., MBSR, certified yoga therapy), trained instructors, safety monitoring, and adaptable delivery in clinical and educational settings. Emerging digital tools – such as mobile apps, virtual reality, wearables, and EEG/HRV feedback – enable scalable access and precision tracking. Future priorities include large longitudinal RCTs for dementia-risk reduction, multimodal mechanistic studies integrating connectomics and endocrine–immune biomarkers, and evaluation of synergistic combinations (e.g., exercise plus meditation or neurofeedback-integrated cognitive training).

Comparable studies

Other narrative reviews on meditation, most cited first.

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