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Mediators of Mindfulness-Based Interventions in Children and Young People: A Systematic Review and Meta-analysis

Lian Liu, Tang Jy, Jia-Qi Xu

Mindfulness May 16, 2026 DOI: 10.1007/s12671-026-02868-w (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Systematic review and meta-analysis Peer reviewed
Sample size 14,690
Population Children, adolescents, and tertiary students
Topics Meditation
Keywords Psychological intervention Mental health Mediation Narrative review Trait Medline Clinical psychology Psychotherapist Public health Developmental psychology
Key findings In tertiary students, trait mindfulness, mindful attention and awareness, mindful acceptance and decentering, and self-compassion each mediated the effect of mindfulness-based interventions on reducing stress, with small effect sizes.

Abstract

Abstract Objectives Mindfulness-based interventions (MBIs) for children and young people have gained recognition in enhancing their mental health. Understanding how MBIs may exert their effects is essential for optimizing mindfulness programs in young people. This systematic review and meta-analysis aimed to identify and synthesize mediators of MBIs in youngsters.

Method: A comprehensive search of PubMed, PsycINFO, Scopus, and EMBASE identified 4435 records published from January 2000 to November 2024. Forty-two studies involving 14,690 participants were included. Due to limited studies in children and adolescents, the meta-analyses focused on tertiary students. Narrative synthesis was also conducted.

Results: In tertiary students, trait mindfulness ( ES = − 0.15, 95% CI − 0.26 to − 0.04), mindful attention and awareness ( ES = − 0.12, 95% CI − 0.20 to − 0.05), mindful acceptance and decentering ( ES = − 0.16, 95% CI − 0.27 to − 0.05), and self-compassion ( ES = − 0.20, 95% CI − 0.32 to − 0.08) acted as mediators between MBIs and stress. Narrative synthesis found insufficient evidence to support the indirect effects of these mediators on other mental health outcomes for tertiary students. Mediation studies of self-regulation and biased self-processing generated mixed results. There was some but insufficient evidence to support the mediators on mental health of adolescents and children.

Conclusions: This review supported the benefits of MBIs through improved mindfulness skills and self-compassion in tertiary students’ mental health. More studies in children and adolescents were needed to compare whether mechanisms varied across age groups. Preregistration The review protocol was registered on PROSPERO (Registration No: CRD42023495622).

Comparable studies

Other systematic reviews and meta-analyses on meditation, most cited first.

Study Year Design Participants
Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations 2014 Meta-analysis n = 3,515
Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis Healthy subjects 2009 Systematic review and meta-analysis
The psychological effects of meditation: A meta-analysis. Nonclinical groups of adult meditators 2012 Meta-analysis n = 163
Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse Adults with recurrent depression in full or partial remission 2016 Meta-analysis of individual patient data from randomized controlled trials n = 1,258
Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials 2011 Systematic review

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