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Metacognitive awareness and prevention of relapse in depression: Empirical evidence.

John D. Teasdale, Richard G. Moore, Hazel Hayhurst, Marie Pope, Susan P. Williams, Zindel V. Segal

Journal of Consulting and Clinical Psychology 2002 DOI: 10.1037//0022-006x.70.2.275 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational cohort with intervention components Peer reviewed
Population Residually depressed patients and nondepressed controls; recovered depressed patients
Intervention Cognitive therapy
Topics Meditation Depression
Keywords Metacognition Mindfulness-based cognitive therapy Clinical psychology Depression economics Feeling Relapse prevention Psychotherapist
Citations 966
Key findings Cognitive therapy and mindfulness-based cognitive therapy reduce depressive relapse by increasing metacognitive awareness, not by changing belief in thought content.

Abstract

Metacognitive awareness is a cognitive set in which negative thoughts/feelings are experienced as mental events, rather than as the self. The authors hypothesized that (a) reduced metacognitive awareness would be associated with vulnerability to depression and (b) cognitive therapy (CT) and mindfulness-based CT (MBCT) would reduce depressive relapse by increasing metacognitive awareness. They found (a) accessibility of metacognitive sets to depressive cues was less in a vulnerable group (residually depressed patients) than in nondepressed controls; (b) accessibility of metacognitive sets predicted relapse in residually depressed patients; (c) where CT reduced relapse in residually depressed patients, it increased accessibility of metacognitive sets; and (d) where MBCT reduced relapse in recovered depressed patients, it increased accessibility of metacognitive sets. CT and MBCT may reduce relapse by changing relationships to negative thoughts rather than by changing belief in thought content.

Comparable studies

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Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report Patients with a depressive disorder 2015 Observational study
Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder Patients with treatment-resistant major depressive disorder 2012 Observational cohort n = 30
Altered peripheral immune profiles in treatment-resistant depression: response to ketamine and prediction of treatment outcome Healthy controls and actively depressed patients with treatment-resistant depression... 2017 Observational cohort n = 59
Mindfulness-based Stress Reduction (MBSR) Reduces Anxiety, Depression, and Suicidal Ideation in Veterans Veterans at an urban Veterans Health Administration medical facility 2014 Naturalistic study n = 79

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