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Mindfulness‐Based Cognitive Therapy for Nonremitted Patients with Bipolar Disorder

Thilo Deckersbach, Britta K. Hölzel, Lori Eisner, Jonathan P. Stange, Andrew Peckham, Darin D. Dougherty, Scott L. Rauch, Sara W. Lazar, Andrew A. Nierenberg

CNS Neuroscience & Therapeutics April 2, 2011 DOI: 10.1111/j.1755-5949.2011.00236.x (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Pre-post intervention with follow-up Peer reviewed
Sample size 12
Population Individuals with DSM-IV bipolar disorder
Intervention Mindfulness-based cognitive therapy
Duration 12 group sessions, 3-month follow-up
Topics Meditation
Keywords Bipolar disorder Mood Mania Psychosocial Clinical psychology Affect linguistics Mindfulness-based cognitive therapy Depression economics Cognition Psychotherapist
Citations 130
Key points MBCT for bipolar disorder was associated with increased mindfulness, reduced residual depressive symptoms, and improved emotion regulation, well-being, positive affect, and psychosocial functioning at end of treatment and 3-month follow-up.

Abstract

Introduction: Bipolar disorder is characterized by recurrent episodes of depression and/or mania along with interepisodic mood symptoms that interfere with psychosocial functioning. Despite periods of symptomatic recovery, many individuals with bipolar disorder continue to experience substantial residual mood symptoms that often lead to the recurrence of mood episodes.

Aims: This study explored whether a new mindfulness-based cognitive therapy (MBCT) for bipolar disorder would increase mindfulness, reduce residual mood symptoms, and increase emotion-regulation abilities, psychological well-being, positive affect, and psychosocial functioning. Following a baseline clinical assessment, 12 individuals with DSM-IV bipolar disorder were treated with 12 group sessions of MBCT.

Results: At the end of treatment, as well as at the 3 months follow-up, participants showed increased mindfulness, lower residual depressive mood symptoms, less attentional difficulties, and increased emotion-regulation abilities, psychological well-being, positive affect, and psychosocial functioning.

Conclusions: These findings suggest that treating residual mood symptoms with MBCT may be another avenue to improving mood, emotion regulation, well-being, and functioning in individuals with bipolar disorder.

Comparable studies

Other non-randomized and open-label trials on meditation, most cited first.

Study Year Design Participants
Mindfulness-Based Stress Reduction in Relation to Quality of Life, Mood, Symptoms of Stress, and Immune Parameters in Breast and Prostate Cancer Outpatients Early-stage breast and prostate cancer patients 2003 Pre-post intervention study n = 59
Exploring self‐compassion and empathy in the context of mindfulness‐based stress reduction (MBSR) Community sample 2010 Pre-post intervention study
Mindfulness-Based Stress Reduction Lowers Psychological Distress In Medical Students Second-year medical students 2003 Prospective nonrandomized cohort-controlled study n = 302
Intensive meditation training, immune cell telomerase activity, and psychological mediators. Retreat participants and matched controls 2011 Controlled trial with wait-list control group n = 60
The Effectiveness of Mindfulness Training for Children with ADHD and Mindful Parenting for their Parents Children aged 8-12 with ADHD and their parents 2011 Within-group waitlist controlled trial n = 22

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