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Towards an Explanation of Subjective Ketamine Experiences among Young Injection Drug Users.

Stephen E Lankenau, Bill Sanders, Jennifer Jackson Bloom, Dodi Hathazi

Addiction Research & Theory 2008 DOI: 10.1080/16066350801983749 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Qualitative study Peer reviewed
Sample size 213
Population Young injection drug users with histories of ketamine use recruited in New York, New Orleans, and Los Angeles
Topics Esketamine Ketamine
Key findings The authors report that six factors shaped both positive and negative ketamine experiences: polydrug use, drug use history, mode of administration, quantity and quality of ketamine, user group, and setting. Most subjective experiences during any given ketamine event were shaped by combinations of these factors, and experiences were particularly influenced by a lifestyle characterized by homelessness and traveling.

Abstract

Ketamine is a dissociative anesthetic with powerful sedative and hallucinogenic properties. Despite the wide variability in reported subjective experiences, no study has attempted to describe the particular factors that shape these experiences. This manuscript is based upon a sample of 213 young injection drug users recruited in New York, New Orleans, and Los Angeles with histories of ketamine use. Qualitative interviews focused on specific ketamine events, such as first injection of ketamine, most recent injection of ketamine, and most recent experience sniffing ketamine. Findings indicate that six factors impacted both positive and negative ketamine experiences: polydrug use, drug using history, mode of administration, quantity and quality of ketamine, user group, and setting. Most subjective experiences during any given ketamine event were shaped by a combination of these factors. Additionally, subjective ketamine experiences were particularly influenced by a lifestyle characterized by homelessness and traveling.

Comparable studies

Other qualitative studies on ketamine, most cited first.

Study Year Design Participants
Ketamine for Depression, 4: In What Dose, at What Rate, by What Route, for How Long, and at What Frequency? 2017 Qualitative review
Holding on or letting go? Patient experiences of control, context, and care in oral esketamine treatment for treatment-resistant depression: A qualitative study. Patients with treatment-resistant depression participating in off-label oral esketamine... 2022 Qualitative study n = 17
A Cohort-Based Case Report: The Impact of Ketamine-Assisted Therapy Embedded in a Community of Practice Framework for Healthcare Providers With PTSD and Depression Healthcare providers 2022 Quality improvement evaluation with mixed methods n = 94
Predictors of Psychedelic Experience: A Thematic Analysis First-person reports of psychedelic use from the Erowid database (six reports each for... 2022 Thematic analysis n = 22
Expert Opinion on Psychedelic-Assisted Psychotherapy for People with Psychopathological Psychotic Experiences and Psychotic Disorders Experts in psychiatry, clinical psychology, medicine, and psychedelic effects 2024 Qualitative study n = 12

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