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Demystifying Psychedelic Treatments in Psychiatry: Is Ego Dissolution the Solution?

Michael Avissar, A. J. Ambrose

Psychiatric News April 1, 2022 DOI: 10.1176/appi.pn.2022.04.4.35 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics News report Peer reviewed
Topics Ego dissolution
Key points Reports that interest in psychedelics is growing in clinical and research communities, as reflected in sessions at the APA Annual Meeting. It states that a growing body of research suggests psychedelic compounds may be useful for treating certain disorders, and describes classic psychedelics as those whose effects are primarily mediated by the serotonin 5HT2A receptor.

Abstract

A growing body of research suggests that psychedelic compounds may be useful for treating patients with certain disorders. As highlighted by several sessions at the APA Annual meeting, there’s a growing renewed interest in psychedelics, which are compounds that induce changes in thought, perception, and mood, in the clinical and research communities. Classic psychedelics refer to a subset whose mind-manifesting and hallucinogenic effects are primarily mediated by the serotonin receptor, 5HT2A: tryptamines (for example, LSD, psilocybin, DMT, and 5-MeO-DMT), and phenethylamines (for example, MDMA and mescaline).

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