[Endogenous depressions with religious experience].
G I Kopeyko, E V Gedevani, O A Borisova, F M Shankov, B V Smirnova, V G Kaleda
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 2021 DOI: 10.17116/jnevro202112105255 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Sample size | 115 |
| Population | Patients with depression and religious distress in affective disorders or schizophrenia |
| Topics | Depression |
| Keywords | Endogenous depression Godforsakenness Guilt and sinfulness Pathological pseudo-religiosity Religious experiences Spiritual hypochondria Suicidal risks |
| Key findings | Depressive states with a religious facade often remain unrecognized, leading to increased suicidal activity, and require early diagnosis and specific treatment. |
Abstract
To identify the specifics of psychopathology and phenomenology of religious experience in depressed patients, for early diagnosis of mental disorders masked by a «religious facade», and prevention of suicidal activity. The study included 115 patients (41 men, 74 women) with depression contained religious distress in affective disorders (38 observations) and schizophrenia (77 observations), F31.3, F31.4, F32.1, F32.2, F33.1, F33.2 and F20.0, F20.4, F21 according to ICD-10. According the psychopathological structure of depressive states, five types of depression were identified. The predominant type was melancholic depression (61%). Based on characteristics of religious experience, types of depressions were distinguished as follows: with congruent religious ideas of guilt and sinfulness; with the loss of «living» faith, God-forsakenness; with overvalued doubts about the choice of faith; and with «spiritual hypochondria». Mental disorders, in particular depressive states, which have a religious «facade» often remain unrecognized due to the specific religious content, which often leads to severe and sometimes irreversible consequences as suicidal activity. Thus, these conditions require early diagnosis and specific approaches to the treatment.
Comparable studies
Other observational and cohort studies on depression, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Metacognitive awareness and prevention of relapse in depression: Empirical evidence. Residually depressed patients and nondepressed controls; recovered depressed patients | 2002 | Observational cohort with intervention components | |
| Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms. Patients with treatment-resistant depression | 2017 | Observational cohort | n = 19 |
| Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report Patients with a depressive disorder | 2015 | Observational study | |
| Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder Patients with treatment-resistant major depressive disorder | 2012 | Observational cohort | n = 30 |
| Altered peripheral immune profiles in treatment-resistant depression: response to ketamine and prediction of treatment outcome Healthy controls and actively depressed patients with treatment-resistant depression... | 2017 | Observational cohort | n = 59 |