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Some Religious and Spiritual Experiences Associated with Depression Resemble Hypomania/Mania

Ari Brouwer, Charles L. Raison

July 1, 2026 preprint DOI: 10.31234/osf.io/ew5mh_v1 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Content analysis and phenomenological analysis
Sample size 249
Population First-person reports of religious and spiritual experiences associated with depression
Topics Depression
Keywords Psychopathology Depression economics Psychosocial Mental health Cognition Relevance law Perception Spirituality Interpretation philosophy Psychotherapist Clinical psychology Hypomania Praxis Interpretative phenomenological analysis Depressive symptoms Function biology Mood
Key points Some religious and spiritual experiences associated with depression resemble hypomania or mania, involving long-duration positive emotional and perceptual states, and may either eliminate depression or be linked to mental health problems.

Abstract

This paper explores whether some religious and spiritual experiences (RSEs) associated with depression resemble hypomania/mania. Content analysis and phenomenological analysis were used to characterize first-person RSE reports associated with depression (N = 249). Findings reveal that some RSEs that follow depression are characterized by long-duration states (lasting days to weeks) of positive emotion, cognitive clarity, and a sense that the external environment is imbued with extra positive emotional and perceptual qualities (e.g., love, beauty, light, vividness). These long-duration positive states are not always preceded by discrete visionary or hallucinatory phenomena, suggesting that hypomanic/manic-like experiences, in addition to psychotic-like experiences, bear relevance to the study of RSEs. Some RSEs that resemble hypomania reportedly annihilate depression or prevent its recurrence. Other reports of recurrent RSEs associated with depression refer to mental health and social problems. Relational features of certain RSEs, such as experiences of unconditional love, acceptance, and support, may relate to better outcomes associated with RSEs relative to typical psychopathological experiences. This interpretation is consistent with the idea that RS traditions function in part, like psychotherapeutic traditions, to promote mental well-being and to protect against psychosocial dysfunction.

Comparable studies

Other qualitative studies on depression, most cited first.

Study Year Design Participants
Patients’ Accounts of Increased “Connectedness” and “Acceptance” After Psilocybin for Treatment-Resistant Depression Patients with treatment-resistant depression enrolled in an open-label trial of psilocybin 2017 Qualitative study n = 20
An exploratory mixed methods study of the acceptability and effectiveness of mindfulness -based cognitive therapy for patients with active depression and anxiety in primary care Primary care patients with recurrent depression or recurrent depression and anxiety 2006 Exploratory mixed methods study n = 13
A qualitative study of mindfulness‐based cognitive therapy for depression Participants in mindfulness-based cognitive therapy in a mental-health context 2001 Qualitative study n = 7
Ketamine for Depression, 4: In What Dose, at What Rate, by What Route, for How Long, and at What Frequency? 2017 Qualitative review
Abnormal Time Experiences in Major Depression: An Empirical Qualitative Study Patients affected by affective and schizophrenic disorders 2016 Qualitative study n = 550

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