Default mode network connectivity is related to pain frequency and intensity in adolescents
Scott A. Jones, A. Morales, A. Holley, Anna Wilson, B. Nagel
NeuroImage: Clinical June 25, 2020 DOI: 10.1016/j.nicl.2020.102326 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational study Peer reviewed |
|---|---|
| Population | Adolescents |
| Topics | Default mode network |
| Key findings | Pain symptoms in adolescents are associated with default mode network connectivity, with more frequent pain linked to greater connectivity to the superior frontal gyrus and higher pain intensity linked to less connectivity to the cerebellum. |
Abstract
Highlights • Pain symptoms in adolescents are associated with default mode network connectivity.• More frequent pain is associated with more connectivity to the superior frontal gyrus.• Higher pain intensity is associated with less connectivity to the cerebellum.
Comparable studies
Other observational and cohort studies on default mode network, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| A default mode of brain function Normal adult human brain | 2001 | Observational study | |
| Resting-State Functional Connectivity Reflects Structural Connectivity in the Default Mode Network Healthy subjects | 2008 | Observational cohort | |
| Meditation experience is associated with increased cortical thickness Participants with extensive Insight meditation experience and matched controls | 2005 | Observational cohort | n = 20 |
| Meditation experience is associated with differences in default mode network activity and connectivity Experienced meditators and matched meditation-naive controls | 2011 | Observational cohort | |
| The precuneus/posterior cingulate cortex plays a pivotal role in the default mode network: Evidence from a partial correlation network analysis Healthy subjects | 2008 | Observational study |
Citations in the library
Cited by 3
- The impact of an app-delivered mindfulness-based intervention on resting-state functional connectivity in pediatric concussion: a pilot study Frontiers in Neuroscience September 17, 2026
- Yoga Nidra and Pain: A between-, within-Group Meta-Analysis and Dose Response Meta-Regression Complementary Medicine Research November 4, 2025
- The Role of Pain Frequency in the Divergent Associations Between Cannabis Use and Default Mode Network Connectivity
Cites 4
- Functional Reorganization of the Default Mode Network across Chronic Pain Conditions PLoS One September 2, 2014
- Default mode network connectivity: effects of age, sex, and analytic approach Neuroreport May 28, 2008
- Disrupted default mode network connectivity in migraine without aura The Journal of Headache and Pain November 8, 2013
- Disruption of default mode network dynamics in acute and chronic pain states NeuroImage: Clinical October 19, 2017