Cortical Structure in Nodes of the Default Mode Network estimates General Intelligence
Abhinav Yadav, Archana Purushotham
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort |
|---|---|
| Sample size | 44 |
| Population | Young, healthy adults |
| Topics | Default mode network |
| Key findings | Cortical thickness and gyrification in medial and temporal nodes of the Default Mode Network reliably correlate with general intelligence and can estimate individual g scores. |
Abstract
A growing number of studies implicate functional brain networks in intelligence, but it is unclear if network nodal structure relates to intelligence. Using MRI, we studied the relationship of the general intelligence factor (g) with cortical thickness (CT), local gyrification index (LGI) and voxel-based morphometry in the nodes of the Default Mode Network (DMN) and Task-Positive Network (TPN) in a cohort of 44 young, healthy adults. Employing a novel strategy, we performed repeated analyses with multiple sets of g estimates to remove false positives. CT and LGI in medial and temporal nodes of the DMN were reliably correlated with g (P<0.05; r: 0.31-0.41). A linear regression model developed with these parameters (adj. R2: 0.15-0.40) could estimate individual g scores. Cortical thickness and gyrification in key nodes of the Default Mode Network correlate with intelligence and can estimate g in individual subjects.
Comparable studies
Other observational and cohort studies on default mode network, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| A default mode of brain function Normal adult human brain | 2001 | Observational study | |
| Resting-State Functional Connectivity Reflects Structural Connectivity in the Default Mode Network Healthy subjects | 2008 | Observational cohort | |
| Meditation experience is associated with increased cortical thickness Participants with extensive Insight meditation experience and matched controls | 2005 | Observational cohort | n = 20 |
| Meditation experience is associated with differences in default mode network activity and connectivity Experienced meditators and matched meditation-naive controls | 2011 | Observational cohort | |
| The precuneus/posterior cingulate cortex plays a pivotal role in the default mode network: Evidence from a partial correlation network analysis Healthy subjects | 2008 | Observational study |
Citations in the library
Cites 3
- A default mode of brain function Proceedings of the National Academy of Sciences January 16, 2001
- The Brain's Default Mode Network Annual Review of Neuroscience May 4, 2015
- Representing Representation: Integration between the Temporal Lobe and the Posterior Cingulate Influences the Content and Form of Spontaneous Thought. PLoS One August 25, 2016