Type 2 diabetes is related to neurochemical alterations in the default mode network: An exploratory cross-sectional magnetic resonance spectroscopy study.
Neuroimage April 22, 2026 DOI: 10.1016/j.neuroimage.2026.121949 (opens in new tab) via PubMed
Summary
AI-generated from the abstractType 2 diabetes is associated with neurochemical changes in the default mode network of the brain, according to an exploratory cross-sectional study using magnetic resonance spectroscopy. The findings suggest that individuals with type 2 diabetes may have altered metabolite levels in brain regions involved in self-referential thought and memory, which could contribute to cognitive decline often seen in the condition. The study indicates a link between diabetes and brain chemistry, but the cross-sectional design limits causal conclusions.
Study at a glance
| Characteristics | Cross-sectional study Peer reviewed |
|---|---|
| Key finding | Type 2 diabetes is related to neurochemical alterations in the default mode network. |
Abstract
Type 2 diabetes is related to neurochemical alterations in the default mode network: An exploratory cross-sectional magnetic resonance spectroscopy study.