Systematic Reviews of Mindfulness and Acceptance and Commitment Therapy for Alcohol Use Disorder: Should we be using Third Wave Therapies?
Simon P. Byrne, Paul Haber, A. Baillie, D. Costa, V. Fogliati, Kirsten Morley
Alcohol and Alcoholism March 1, 2019 DOI: 10.1093/alcalc/agy089 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Systematic review Randomized Peer reviewed |
|---|---|
| Population | Adults with alcohol use disorders or alcohol use causing impairment |
| Topics | Addiction Meditation |
| Key findings | Third wave therapies (mindfulness and ACT) are better than no treatment or treatments of minimal efficacy for AUDs and may be comparable to effective psychosocial treatments. |
Abstract
Aims: Third wave therapies have shown efficacy for treating emotional disorders and potential for treating substance use disorders. There is developing interest in whether they can more specifically be used for treating alcohol use disorders (AUDs). We were interested in whether third wave therapies have value alongside current evidence-based psychosocial treatments for AUDs.
Method: We conducted systematic reviews of third wave therapies for AUDs. We searched PsycINFO, Embase and Medline for peer reviewed journal articles where mindfulness or Acceptance and Commitment Therapy (ACT) were used to treat adults with AUDs or alcohol use that caused impairment.
Results: We identified 11 studies where mindfulness was used for treating AUDs and 6 where ACT was used for AUDs. The studies identified included RCTs, non-randomized controlled studies and uncontrolled studies. We found preliminary support that both third wave therapies are better than no treatment, treatments of minimal efficacy, as well as some evidence they are comparable to effective psychosocial treatments for AUDs.
Conclusions: We conclude ACT and mindfulness provide an alternative to existing treatments, particularly for patients who have not responded to, or have disengaged from, standard treatments. We also found some evidence ACT and mindfulness are useful for comorbid mental health conditions. Yet while these results are promising, further research is needed to determine their utility, ideally employing randomized-controlled designs, larger clinical samples and longer follow-ups. Furthermore, few studies in this review directly compared third wave therapies to first line treatments, making it difficult to determine their relative efficacy.
Comparable studies
Other systematic reviews and meta-analyses on addiction, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Ketamine use: a review Ketamine users | 2011 | Systematic review | |
| Mindfulness Meditation for Substance Use Disorders: A Systematic Review Individuals with substance use disorders | 2009 | Systematic review | |
| Mindfulness-Based Interventions for the Treatment of Substance and Behavioral Addictions: A Systematic Review | 2018 | Systematic review | |
| Ketamine for the treatment of mental health and substance use disorders: comprehensive systematic review | 2021 | Systematic review | |
| Therapeutic Use of LSD in Psychiatry: A Systematic Review of Randomized-Controlled Clinical Trials Patients with psychiatric disorders, primarily alcoholism | 2020 | Systematic review | n = 567 |
Citations in the library
Cited by 8
- Overview of Alcohol Use Disorder. American Journal of Psychiatry August 1, 2023
- The potential of 5‐methoxy‐N,N‐dimethyltryptamine in the treatment of alcohol use disorder: A first look at therapeutic mechanisms of action Addiction Biology April 1, 2024
- Psilocybin-assisted therapy for severe alcohol use disorder: protocol for a double-blind, randomized, placebo-controlled, 7-month parallel-group phase II superiority trial. BMC Psychiatry January 26, 2024
- Psychedelics for Alcohol Use Disorder: A Narrative Review with Candidate Mechanisms of Action. CNS Drugs July 10, 2025
- Psilocybin-Assisted Therapy for Severe Alcohol Use Disorder: Protocol for a Double-Blind, Randomized, Placebo-Controlled, 7-month Parallel-Group Phase II Superiority Trial Research Square January 4, 2024
and 3 more in the library
Cites 8
- Mindfulness Meditation for Alcohol Relapse Prevention: A Feasibility Pilot Study Journal of Addiction Medicine May 4, 2008
- Ultra-Brief Mindfulness Training Reduces Alcohol Consumption in At-Risk Drinkers: A Randomized Double-Blind Active-Controlled Experiment The International Journal of Neuropsychopharmacology July 28, 2017
- Retraining the addicted brain: a review of hypothesized neurobiological mechanisms of mindfulness-based relapse prevention. Psychology of Addictive Behaviors July 9, 2012
- Mindfulness-Oriented Recovery Enhancement for Alcohol Dependence: Therapeutic Mechanisms and Intervention Acceptability. Journal of social work practice in the addictions July 1, 2012
- Mindfulness practice leads to increases in regional brain gray matter density Psychiatry Research November 10, 2010
and 3 more in the library